Single-cell RNA-seq analysis reveals microenvironmental infiltration of myeloid cells and pancreatic prognostic markers in PDAC

Single-cell RNA-seq analysis reveals microenvironmental infiltration of myeloid cells and pancreatic prognostic markers in PDAC

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has a heterogeneous make-up of myeloid cells that influences the therapeutic response and prognosis. However, understanding the myeloid cell at both a genetic and cellular level remains a significant challenge. Methods Single-cell RNA seque...

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Bibliographic Details
Main Authors: Yanying Fan, Lili Wu, Xinyu Qiu, Han Shi, Longhang Wu, Juan Lin, Jie Lin, Tianhong Teng
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Discover Oncology
Subjects:
PADC
Myeloid
Prognosis
scRNA-seq
Risk model
Online Access:https://doi.org/10.1007/s12672-025-01830-x
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