Optimal Control of Multiple Transmission of Water-Borne Diseases

A controlled SIWR model was considered which was an extension of the simple SIR model by adjoining a compartment (𝑊) that tracks the pathogen concentration in the water. New infections arise both through exposure to contaminated water as well as by the classical SIR person-person transmission pathwa...

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Main Authors: G. Devipriya, K. Kalaivani
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Mathematics and Mathematical Sciences
Online Access:http://dx.doi.org/10.1155/2012/421419
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author G. Devipriya
K. Kalaivani
author_facet G. Devipriya
K. Kalaivani
author_sort G. Devipriya
collection DOAJ
description A controlled SIWR model was considered which was an extension of the simple SIR model by adjoining a compartment (𝑊) that tracks the pathogen concentration in the water. New infections arise both through exposure to contaminated water as well as by the classical SIR person-person transmission pathway. The controls represent an immune boosting and pathogen suppressing drugs. The objective function is based on a combination of minimizing the number of infected individuals and the cost of the drugs dose. The optimal control is obtained by solving the optimality system which was composed of four nonlinear ODEs with initial conditions and four nonlinear adjoint ODEs with transversality conditions. The results were analysed and interpreted numerically using MATLAB.
format Article
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institution Kabale University
issn 0161-1712
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language English
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series International Journal of Mathematics and Mathematical Sciences
spelling doaj-art-f2aec22d59b24372ae9c5a5382434a342025-02-03T06:08:47ZengWileyInternational Journal of Mathematics and Mathematical Sciences0161-17121687-04252012-01-01201210.1155/2012/421419421419Optimal Control of Multiple Transmission of Water-Borne DiseasesG. Devipriya0K. Kalaivani1P. G. Department of Mathematics, Women's Christian College, Chennai 600006, IndiaP. G. Department of Mathematics, Women's Christian College, Chennai 600006, IndiaA controlled SIWR model was considered which was an extension of the simple SIR model by adjoining a compartment (𝑊) that tracks the pathogen concentration in the water. New infections arise both through exposure to contaminated water as well as by the classical SIR person-person transmission pathway. The controls represent an immune boosting and pathogen suppressing drugs. The objective function is based on a combination of minimizing the number of infected individuals and the cost of the drugs dose. The optimal control is obtained by solving the optimality system which was composed of four nonlinear ODEs with initial conditions and four nonlinear adjoint ODEs with transversality conditions. The results were analysed and interpreted numerically using MATLAB.http://dx.doi.org/10.1155/2012/421419
spellingShingle G. Devipriya
K. Kalaivani
Optimal Control of Multiple Transmission of Water-Borne Diseases
International Journal of Mathematics and Mathematical Sciences
title Optimal Control of Multiple Transmission of Water-Borne Diseases
title_full Optimal Control of Multiple Transmission of Water-Borne Diseases
title_fullStr Optimal Control of Multiple Transmission of Water-Borne Diseases
title_full_unstemmed Optimal Control of Multiple Transmission of Water-Borne Diseases
title_short Optimal Control of Multiple Transmission of Water-Borne Diseases
title_sort optimal control of multiple transmission of water borne diseases
url http://dx.doi.org/10.1155/2012/421419
work_keys_str_mv AT gdevipriya optimalcontrolofmultipletransmissionofwaterbornediseases
AT kkalaivani optimalcontrolofmultipletransmissionofwaterbornediseases