A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
OBJECTIVE: Efficient gas exchange across the alveolar membrane requires a dry air space. At birth, active Na+ transport provides the major driving force for absorption of fetal lung liquid, and during adult life, similar transport mechanisms balance fluid exchange across the alveolarcapillary membra...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1994-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/1994/357537 |
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| _version_ | 1832563394486468608 |
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| author | Beverley A Orser Jeffrey D Edelson |
| author_facet | Beverley A Orser Jeffrey D Edelson |
| author_sort | Beverley A Orser |
| collection | DOAJ |
| description | OBJECTIVE: Efficient gas exchange across the alveolar
membrane requires a dry air space. At birth, active Na+
transport provides the major driving force for absorption of
fetal lung liquid, and during adult life, similar transport
mechanisms balance fluid exchange across the alveolarcapillary
membrane. A cation channel, previously identified
in fetal alveolar epithe lium, may represent one of several
pathways which regulate apical-basal transepithelial Na+
flux. The purpose of this study was to determine if cation
channels are also present in adult alveolar epithelial cells. |
| format | Article |
| id | doaj-art-f2acc7cb82414884aef4a82e688f46a7 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 1994-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-f2acc7cb82414884aef4a82e688f46a72025-02-03T01:20:19ZengWileyCanadian Respiratory Journal1198-22411994-01-011212913610.1155/1994/357537A Nonselective Cation Channel in Adult Alveolar Epithelial CellsBeverley A Orser0Jeffrey D Edelson1Department of Anaesthesia, Sunnybrook Health Science Centre, Department of Physiology, University of Toronto, Toronto, Ontario, CanadaDepartment of Anaesthesia, Sunnybrook Health Science Centre, Department of Physiology, University of Toronto, Toronto, Ontario, CanadaOBJECTIVE: Efficient gas exchange across the alveolar membrane requires a dry air space. At birth, active Na+ transport provides the major driving force for absorption of fetal lung liquid, and during adult life, similar transport mechanisms balance fluid exchange across the alveolarcapillary membrane. A cation channel, previously identified in fetal alveolar epithe lium, may represent one of several pathways which regulate apical-basal transepithelial Na+ flux. The purpose of this study was to determine if cation channels are also present in adult alveolar epithelial cells.http://dx.doi.org/10.1155/1994/357537 |
| spellingShingle | Beverley A Orser Jeffrey D Edelson A Nonselective Cation Channel in Adult Alveolar Epithelial Cells Canadian Respiratory Journal |
| title | A Nonselective Cation Channel in Adult Alveolar Epithelial Cells |
| title_full | A Nonselective Cation Channel in Adult Alveolar Epithelial Cells |
| title_fullStr | A Nonselective Cation Channel in Adult Alveolar Epithelial Cells |
| title_full_unstemmed | A Nonselective Cation Channel in Adult Alveolar Epithelial Cells |
| title_short | A Nonselective Cation Channel in Adult Alveolar Epithelial Cells |
| title_sort | nonselective cation channel in adult alveolar epithelial cells |
| url | http://dx.doi.org/10.1155/1994/357537 |
| work_keys_str_mv | AT beverleyaorser anonselectivecationchannelinadultalveolarepithelialcells AT jeffreydedelson anonselectivecationchannelinadultalveolarepithelialcells AT beverleyaorser nonselectivecationchannelinadultalveolarepithelialcells AT jeffreydedelson nonselectivecationchannelinadultalveolarepithelialcells |