A Nonselective Cation Channel in Adult Alveolar Epithelial Cells
OBJECTIVE: Efficient gas exchange across the alveolar membrane requires a dry air space. At birth, active Na+ transport provides the major driving force for absorption of fetal lung liquid, and during adult life, similar transport mechanisms balance fluid exchange across the alveolarcapillary membra...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1994-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/1994/357537 |
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| Summary: | OBJECTIVE: Efficient gas exchange across the alveolar
membrane requires a dry air space. At birth, active Na+
transport provides the major driving force for absorption of
fetal lung liquid, and during adult life, similar transport
mechanisms balance fluid exchange across the alveolarcapillary
membrane. A cation channel, previously identified
in fetal alveolar epithe lium, may represent one of several
pathways which regulate apical-basal transepithelial Na+
flux. The purpose of this study was to determine if cation
channels are also present in adult alveolar epithelial cells. |
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| ISSN: | 1198-2241 |