Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published...
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| Format: | Article |
| Language: | English |
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BioMed Central
2013-09-01
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| Series: | Genomics & Informatics |
| Subjects: | |
| Online Access: | http://genominfo.org/upload/pdf/gni-11-155.pdf |
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| _version_ | 1832569564043411456 |
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| author | Sunghoon Jung Se-Eun Bae Insung Ahn Hyeon S. Son |
| author_facet | Sunghoon Jung Se-Eun Bae Insung Ahn Hyeon S. Son |
| author_sort | Sunghoon Jung |
| collection | DOAJ |
| description | Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published. The reliability of the torsional system, which represents the native processes of structural change in the structural analysis, was partially proven with previous structural alignment studies. Here, a web server providing structural information and analysis based on the backbone torsional representation of a protein structure is newly introduced. The web server offers functions of secondary structure database search, secondary structure calculation, and pair-wise protein structure comparison, based on a backbone torsion angle representation system. Application of the implementation in pair-wise structural alignment showed highly accurate results. The information derived from this web server might be further utilized in the field of ab initio protein structure modeling or protein homology-related analyses. |
| format | Article |
| id | doaj-art-f2ab15b642c646618208ca94192d2471 |
| institution | Kabale University |
| issn | 1598-866X 2234-0742 |
| language | English |
| publishDate | 2013-09-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-f2ab15b642c646618208ca94192d24712025-02-02T20:48:16ZengBioMed CentralGenomics & Informatics1598-866X2234-07422013-09-0111315516010.5808/GI.2013.11.3.15551Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web ServerSunghoon Jung0Se-Eun Bae1Insung Ahn2Hyeon S. Son3Molecular Recognition Research Center, Korea Institute of Science and Technology, Seoul 136-791, Korea.Laboratory of Computational Biology and Bioinformatics, Graduate School of Public Health, Seoul National University, Seoul 151-742, Korea.Bioinformatics Team, Supercomputing Center, Korea Institute of Science and Technology Information, Daejon 305-806, Korea.Laboratory of Computational Biology and Bioinformatics, Graduate School of Public Health, Seoul National University, Seoul 151-742, Korea.Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published. The reliability of the torsional system, which represents the native processes of structural change in the structural analysis, was partially proven with previous structural alignment studies. Here, a web server providing structural information and analysis based on the backbone torsional representation of a protein structure is newly introduced. The web server offers functions of secondary structure database search, secondary structure calculation, and pair-wise protein structure comparison, based on a backbone torsion angle representation system. Application of the implementation in pair-wise structural alignment showed highly accurate results. The information derived from this web server might be further utilized in the field of ab initio protein structure modeling or protein homology-related analyses.http://genominfo.org/upload/pdf/gni-11-155.pdfbackbone torsion angleprotein databasesecondary protein structurestructure alignment |
| spellingShingle | Sunghoon Jung Se-Eun Bae Insung Ahn Hyeon S. Son Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server Genomics & Informatics backbone torsion angle protein database secondary protein structure structure alignment |
| title | Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server |
| title_full | Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server |
| title_fullStr | Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server |
| title_full_unstemmed | Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server |
| title_short | Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server |
| title_sort | protein backbone torsion angle based structure comparison and secondary structure database web server |
| topic | backbone torsion angle protein database secondary protein structure structure alignment |
| url | http://genominfo.org/upload/pdf/gni-11-155.pdf |
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