Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies
Abstract This randomized, controlled trial evaluated the impact of plaque visualization combined with daily tasks on cardiovascular risk profile and included 240 participants with coronary arterial disease. The intervention group received the PreventiPlaque app during the 12-month study period in ad...
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| Format: | Article |
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Nature Portfolio
2025-01-01
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| Series: | npj Digital Medicine |
| Online Access: | https://doi.org/10.1038/s41746-024-01423-y |
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| author | Greta Ullrich Alexander Bäuerle Lisa Maria Jahre Katrin Paldán Jana Rosemeyer Chiara Kalaitzidis Christos Rammos Martin Teufel Tienush Rassaf Julia Lortz |
| author_facet | Greta Ullrich Alexander Bäuerle Lisa Maria Jahre Katrin Paldán Jana Rosemeyer Chiara Kalaitzidis Christos Rammos Martin Teufel Tienush Rassaf Julia Lortz |
| author_sort | Greta Ullrich |
| collection | DOAJ |
| description | Abstract This randomized, controlled trial evaluated the impact of plaque visualization combined with daily tasks on cardiovascular risk profile and included 240 participants with coronary arterial disease. The intervention group received the PreventiPlaque app during the 12-month study period in addition to standard care. The app contained daily tasks that promoted lifestyle modifications and adherence to prescribed medication. It included ultrasound images of participants´ individual carotid plaque, which were updated regularly. The impact of plaque visualization and personalized app usage was evaluated, using a change in the SCORE2 as a primary endpoint. In the intervention group, the SCORE2 was significantly lower after the study period (t(120) = 6.43, p adj < 0.001, d RM = 0.58). This demonstrates the efficacy of the PreventiPlaque app in supporting lifestyle modifications and medication adherence. These findings suggest that personalized mHealth interventions in combination with visual risk communication are valuable tools in secondary prevention. Trial Registration: The study was registered at ClinicalTrials.gov under the identifier NCT05096637 on 27 October 2021 and was approved by the local ethics committee of the University of Duisburg-Essen (20-9157-BO). |
| format | Article |
| id | doaj-art-f2ab000a33624182b6c6a0698a474e0c |
| institution | Kabale University |
| issn | 2398-6352 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Digital Medicine |
| spelling | doaj-art-f2ab000a33624182b6c6a0698a474e0c2025-01-26T12:53:53ZengNature Portfolionpj Digital Medicine2398-63522025-01-01811910.1038/s41746-024-01423-yImpact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologiesGreta Ullrich0Alexander Bäuerle1Lisa Maria Jahre2Katrin Paldán3Jana Rosemeyer4Chiara Kalaitzidis5Christos Rammos6Martin Teufel7Tienush Rassaf8Julia Lortz9Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Hufelandstr. 55Clinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, Virchowstr. 175Clinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, Virchowstr. 175UCT Research, Vorarlberg University of Applied Science, Hochschulstraße 1Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Hufelandstr. 55Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Hufelandstr. 55Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Hufelandstr. 55Clinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, Virchowstr. 175Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Hufelandstr. 55Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center Essen, University of Duisburg-Essen, Hufelandstr. 55Abstract This randomized, controlled trial evaluated the impact of plaque visualization combined with daily tasks on cardiovascular risk profile and included 240 participants with coronary arterial disease. The intervention group received the PreventiPlaque app during the 12-month study period in addition to standard care. The app contained daily tasks that promoted lifestyle modifications and adherence to prescribed medication. It included ultrasound images of participants´ individual carotid plaque, which were updated regularly. The impact of plaque visualization and personalized app usage was evaluated, using a change in the SCORE2 as a primary endpoint. In the intervention group, the SCORE2 was significantly lower after the study period (t(120) = 6.43, p adj < 0.001, d RM = 0.58). This demonstrates the efficacy of the PreventiPlaque app in supporting lifestyle modifications and medication adherence. These findings suggest that personalized mHealth interventions in combination with visual risk communication are valuable tools in secondary prevention. Trial Registration: The study was registered at ClinicalTrials.gov under the identifier NCT05096637 on 27 October 2021 and was approved by the local ethics committee of the University of Duisburg-Essen (20-9157-BO).https://doi.org/10.1038/s41746-024-01423-y |
| spellingShingle | Greta Ullrich Alexander Bäuerle Lisa Maria Jahre Katrin Paldán Jana Rosemeyer Chiara Kalaitzidis Christos Rammos Martin Teufel Tienush Rassaf Julia Lortz Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies npj Digital Medicine |
| title | Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies |
| title_full | Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies |
| title_fullStr | Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies |
| title_full_unstemmed | Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies |
| title_short | Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies |
| title_sort | impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mhealth technologies |
| url | https://doi.org/10.1038/s41746-024-01423-y |
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