Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease
Objectives. Ninety-one fetuses with dilated or hypertrophic cardiomyopathy (DCM, HCM) and myocarditis were studied. Results. Group 1 “DCM” included 19 fetuses: 13 with hydrops (FH) and 5 with associated extracardiac anomalies (ECAs) (15.8%). Group 2 “Myocarditis” included twelve fetuses, having 11 w...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2010/628451 |
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| author | Vlasta Fesslova Maurizio Mongiovì Salvatore Pipitone Jelena Brankovic Laura Villa |
| author_facet | Vlasta Fesslova Maurizio Mongiovì Salvatore Pipitone Jelena Brankovic Laura Villa |
| author_sort | Vlasta Fesslova |
| collection | DOAJ |
| description | Objectives. Ninety-one fetuses with dilated or hypertrophic cardiomyopathy (DCM, HCM) and myocarditis were studied. Results. Group 1 “DCM” included 19 fetuses: 13 with hydrops (FH) and 5 with associated extracardiac anomalies (ECAs) (15.8%). Group 2 “Myocarditis” included twelve fetuses, having 11 with FH. Group 3 “HCM” included sixty fetuses: 26 had associated ECAs, 17 had maternal diabetes, and 17 were “idiopathic”; however, in one case, a metabolic disorder was found postnatally, and 4 had familiarity for HCM. Outcomes. Ten cases opted for termination of pregnancy. Two cases with DCM and 1 with HCM were lost at follow-up. Out of the cases that continued pregnancy, with known follow-up, mortality was 68.75% in Group 1, 63.6% in Group 2, and 31.3% in Group 3 (the majority with severe ECAs). Surviving cases with DCM and myocarditis improved, 2 with HCM worsened, 6 remained stable, and 26 improved or normalized. Conclusions. Our data show more severe prognosis in DCM and myocarditis and forms with severe associated ECAs. |
| format | Article |
| id | doaj-art-f292c00b82b94e538717f1aa53c1613e |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-f292c00b82b94e538717f1aa53c1613e2025-02-03T01:10:31ZengWileyInternational Journal of Pediatrics1687-97401687-97592010-01-01201010.1155/2010/628451628451Features and Outcomes In Utero and after Birth of Fetuses with Myocardial DiseaseVlasta Fesslova0Maurizio Mongiovì1Salvatore Pipitone2Jelena Brankovic3Laura Villa4Center of Fetal Cardiology, Policlinico San Donato IRCCS, Via Morandi 30, San Donato Milanese, 20097 Milan, ItalyDepartment of Pediatric Cardiology, “Casa del Sole” Hospital, 90136 Palermo, ItalyDepartment of Pediatric Cardiology, “Casa del Sole” Hospital, 90136 Palermo, ItalyCenter of Fetal Cardiology, Policlinico San Donato IRCCS, Via Morandi 30, San Donato Milanese, 20097 Milan, ItalyFirst Obstetric and Gynecologic Clinic, University of Milan, 20122 Milan, ItalyObjectives. Ninety-one fetuses with dilated or hypertrophic cardiomyopathy (DCM, HCM) and myocarditis were studied. Results. Group 1 “DCM” included 19 fetuses: 13 with hydrops (FH) and 5 with associated extracardiac anomalies (ECAs) (15.8%). Group 2 “Myocarditis” included twelve fetuses, having 11 with FH. Group 3 “HCM” included sixty fetuses: 26 had associated ECAs, 17 had maternal diabetes, and 17 were “idiopathic”; however, in one case, a metabolic disorder was found postnatally, and 4 had familiarity for HCM. Outcomes. Ten cases opted for termination of pregnancy. Two cases with DCM and 1 with HCM were lost at follow-up. Out of the cases that continued pregnancy, with known follow-up, mortality was 68.75% in Group 1, 63.6% in Group 2, and 31.3% in Group 3 (the majority with severe ECAs). Surviving cases with DCM and myocarditis improved, 2 with HCM worsened, 6 remained stable, and 26 improved or normalized. Conclusions. Our data show more severe prognosis in DCM and myocarditis and forms with severe associated ECAs.http://dx.doi.org/10.1155/2010/628451 |
| spellingShingle | Vlasta Fesslova Maurizio Mongiovì Salvatore Pipitone Jelena Brankovic Laura Villa Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease International Journal of Pediatrics |
| title | Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease |
| title_full | Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease |
| title_fullStr | Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease |
| title_full_unstemmed | Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease |
| title_short | Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease |
| title_sort | features and outcomes in utero and after birth of fetuses with myocardial disease |
| url | http://dx.doi.org/10.1155/2010/628451 |
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