Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch)
This study investigated the effects of dietary supplementation with the probiotic Bacillus pumilus on coho salmon (Oncorhynchus kisutch). A total of 360 juvenile fish, with an average initial weight of 130.75 ± 1.33 g, were randomly assigned to four treatment groups, each with three replicates of...
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| Format: | Article |
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KeAi Communications Co. Ltd.
2025-01-01
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| Series: | Water Biology and Security |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772735124000854 |
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| author | Mengjie Guo Liuqing Meng Fanghui Li Yongqiang Liu Ziqi Zhang Qin Zhang Weiguang Kong |
| author_facet | Mengjie Guo Liuqing Meng Fanghui Li Yongqiang Liu Ziqi Zhang Qin Zhang Weiguang Kong |
| author_sort | Mengjie Guo |
| collection | DOAJ |
| description | This study investigated the effects of dietary supplementation with the probiotic Bacillus pumilus on coho salmon (Oncorhynchus kisutch). A total of 360 juvenile fish, with an average initial weight of 130.75 ± 1.33 g, were randomly assigned to four treatment groups, each with three replicates of 30 fish. The fish were then fed for 70 days using formulated diets containing four concentrations of B. pumilus: 0 (control group), 2 × 106, 4 × 108, and 8 × 1010 CFU/g. We then evaluated growth, nutrient metabolism, immune-related serum biochemical markers, enzyme activity, gene expression, and muscle composition. Additionally, we assessed intestinal histology and microbiota composition. Our findings revealed that B. pumilus significantly improved growth, protein and fat metabolism, and immune function compared to the control group. It also had a positive effect on the structure and function of the intestinal microbiota. The group receiving 4 × 108 CFU/g showed the greatest improvements. Overall, B. pumilus appears to be a promising probiotic for enhancing the health and performance of coho salmon in aquaculture. |
| format | Article |
| id | doaj-art-f28421e0dab24aa6a9db1ab40e33fd05 |
| institution | Kabale University |
| issn | 2772-7351 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | KeAi Communications Co. Ltd. |
| record_format | Article |
| series | Water Biology and Security |
| spelling | doaj-art-f28421e0dab24aa6a9db1ab40e33fd052025-01-27T04:22:41ZengKeAi Communications Co. Ltd.Water Biology and Security2772-73512025-01-0141100313Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch)Mengjie Guo0Liuqing Meng1Fanghui Li2Yongqiang Liu3Ziqi Zhang4Qin Zhang5Weiguang Kong6Guangxi Key Laboratory for Polysaccharide Materials and Modifications, Guangxi Marine Microbial Resources Industrialization Engineering Technology Research Center, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, ChinaGuangxi Key Laboratory for Polysaccharide Materials and Modifications, Guangxi Marine Microbial Resources Industrialization Engineering Technology Research Center, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, ChinaGuangxi Key Laboratory for Polysaccharide Materials and Modifications, Guangxi Marine Microbial Resources Industrialization Engineering Technology Research Center, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, ChinaGuangxi Key Laboratory for Polysaccharide Materials and Modifications, Guangxi Marine Microbial Resources Industrialization Engineering Technology Research Center, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, ChinaGuangxi Key Laboratory for Polysaccharide Materials and Modifications, Guangxi Marine Microbial Resources Industrialization Engineering Technology Research Center, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, ChinaGuangxi Key Laboratory for Polysaccharide Materials and Modifications, Guangxi Marine Microbial Resources Industrialization Engineering Technology Research Center, School of Marine Sciences and Biotechnology, Guangxi Minzu University, Nanning, China; Corresponding author.Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China; Corresponding author.This study investigated the effects of dietary supplementation with the probiotic Bacillus pumilus on coho salmon (Oncorhynchus kisutch). A total of 360 juvenile fish, with an average initial weight of 130.75 ± 1.33 g, were randomly assigned to four treatment groups, each with three replicates of 30 fish. The fish were then fed for 70 days using formulated diets containing four concentrations of B. pumilus: 0 (control group), 2 × 106, 4 × 108, and 8 × 1010 CFU/g. We then evaluated growth, nutrient metabolism, immune-related serum biochemical markers, enzyme activity, gene expression, and muscle composition. Additionally, we assessed intestinal histology and microbiota composition. Our findings revealed that B. pumilus significantly improved growth, protein and fat metabolism, and immune function compared to the control group. It also had a positive effect on the structure and function of the intestinal microbiota. The group receiving 4 × 108 CFU/g showed the greatest improvements. Overall, B. pumilus appears to be a promising probiotic for enhancing the health and performance of coho salmon in aquaculture.http://www.sciencedirect.com/science/article/pii/S2772735124000854Coho salmonB. pumilusNutrition metabolismIntestinal microbiotaImmunity |
| spellingShingle | Mengjie Guo Liuqing Meng Fanghui Li Yongqiang Liu Ziqi Zhang Qin Zhang Weiguang Kong Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch) Water Biology and Security Coho salmon B. pumilus Nutrition metabolism Intestinal microbiota Immunity |
| title | Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch) |
| title_full | Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch) |
| title_fullStr | Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch) |
| title_full_unstemmed | Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch) |
| title_short | Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch) |
| title_sort | effects of dietary bacillus pumilus on the growth intestinal health lipid metabolism and mtor signaling pathway of juvenile coho salmon oncorhynchus kisutch |
| topic | Coho salmon B. pumilus Nutrition metabolism Intestinal microbiota Immunity |
| url | http://www.sciencedirect.com/science/article/pii/S2772735124000854 |
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