Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial
Context. Many breast cancer survivors live with chronic neuropathic pain (CNP) after breast cancer treatment. Despite pharmacological management of CNP, many women continue to report disabling pain and reduced quality of life. Addressing pain with psychosocial interventions as an adjunct to pharmaco...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2022/4020550 |
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| author | Yaadwinder Shergill Danielle B. Rice Eve-Ling Khoo Virginia Jarvis Tinghua Zhang Monica Taljaard Keith G. Wilson Heather Romanow Brittany Glynn Rebecca Small Joshua A. Rash Andra Smith Lynette Monteiro Catherine Smyth Patricia A. Poulin |
| author_facet | Yaadwinder Shergill Danielle B. Rice Eve-Ling Khoo Virginia Jarvis Tinghua Zhang Monica Taljaard Keith G. Wilson Heather Romanow Brittany Glynn Rebecca Small Joshua A. Rash Andra Smith Lynette Monteiro Catherine Smyth Patricia A. Poulin |
| author_sort | Yaadwinder Shergill |
| collection | DOAJ |
| description | Context. Many breast cancer survivors live with chronic neuropathic pain (CNP) after breast cancer treatment. Despite pharmacological management of CNP, many women continue to report disabling pain and reduced quality of life. Addressing pain with psychosocial interventions as an adjunct to pharmacological treatment is often recommended for CNP. Objectives. The purpose of this study was to compare the effects of group-delivered mindfulness-based stress reduction as compared to a waitlist control group among breast cancer survivors living with CNP. Methods. A randomized controlled trial design was applied, and outcomes collected included pain, emotional function, quality of life, and global impression of change. Results. A total of 98 women were randomized and included in analyses. The sample included 49 women in the mindfulness-based stress reduction group, and 49 women in the waitlist control group. The intervention group participants (mean age 51.3 years, standard deviation = 11.4) and waitlist participants (mean age 55.1 years, standard deviation = 9.6) reported an average pain duration of approximately three years. No significant differences were found on the primary outcome of the proportions of women with reduced pain interference scores from the time of randomization to 3 months after the intervention was received. No significant changes were found among secondary outcomes. Conclusion. Our randomized clinical trial did not find significant benefits of group-based mindfulness-based stress reduction for the management of CNP. The current study findings should be replicated and are important to consider given ongoing concerns that nonsignificant results of mindfulness-based stress reduction are often unpublished. |
| format | Article |
| id | doaj-art-f26cc52947d544ecba0d6db8d86f12ba |
| institution | Kabale University |
| issn | 1918-1523 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-f26cc52947d544ecba0d6db8d86f12ba2025-02-03T06:12:24ZengWileyPain Research and Management1918-15232022-01-01202210.1155/2022/4020550Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled TrialYaadwinder Shergill0Danielle B. Rice1Eve-Ling Khoo2Virginia Jarvis3Tinghua Zhang4Monica Taljaard5Keith G. Wilson6Heather Romanow7Brittany Glynn8Rebecca Small9Joshua A. Rash10Andra Smith11Lynette Monteiro12Catherine Smyth13Patricia A. Poulin14The Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteDepartment of Anesthesiology and Pain MedicineDepartment of PsychologyDepartment of PsychologyOttawa Mindfulness ClinicThe Ottawa Hospital Research InstituteThe Ottawa Hospital Research InstituteContext. Many breast cancer survivors live with chronic neuropathic pain (CNP) after breast cancer treatment. Despite pharmacological management of CNP, many women continue to report disabling pain and reduced quality of life. Addressing pain with psychosocial interventions as an adjunct to pharmacological treatment is often recommended for CNP. Objectives. The purpose of this study was to compare the effects of group-delivered mindfulness-based stress reduction as compared to a waitlist control group among breast cancer survivors living with CNP. Methods. A randomized controlled trial design was applied, and outcomes collected included pain, emotional function, quality of life, and global impression of change. Results. A total of 98 women were randomized and included in analyses. The sample included 49 women in the mindfulness-based stress reduction group, and 49 women in the waitlist control group. The intervention group participants (mean age 51.3 years, standard deviation = 11.4) and waitlist participants (mean age 55.1 years, standard deviation = 9.6) reported an average pain duration of approximately three years. No significant differences were found on the primary outcome of the proportions of women with reduced pain interference scores from the time of randomization to 3 months after the intervention was received. No significant changes were found among secondary outcomes. Conclusion. Our randomized clinical trial did not find significant benefits of group-based mindfulness-based stress reduction for the management of CNP. The current study findings should be replicated and are important to consider given ongoing concerns that nonsignificant results of mindfulness-based stress reduction are often unpublished.http://dx.doi.org/10.1155/2022/4020550 |
| spellingShingle | Yaadwinder Shergill Danielle B. Rice Eve-Ling Khoo Virginia Jarvis Tinghua Zhang Monica Taljaard Keith G. Wilson Heather Romanow Brittany Glynn Rebecca Small Joshua A. Rash Andra Smith Lynette Monteiro Catherine Smyth Patricia A. Poulin Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial Pain Research and Management |
| title | Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial |
| title_full | Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial |
| title_fullStr | Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial |
| title_full_unstemmed | Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial |
| title_short | Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial |
| title_sort | mindfulness based stress reduction in breast cancer survivors with chronic neuropathic pain a randomized controlled trial |
| url | http://dx.doi.org/10.1155/2022/4020550 |
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