DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY

New mutants, not described previously, resistant to L-cycloserine and β-chloro-L-alanine were derived from the parental strain Brevibacterium flavum AA5. Their alanine-producing ability was studied. It was found that the resistance to L-cycloserine did not affect the yield of L-alanine significantly...

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Bibliographic Details
Main Authors: G. Ye. Avetisova, L. H. Melkonyan, A. Kh. Chakhalyan, S. Gh. Keleshyan, A. S. Saghyan
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2015-01-01
Series:Вавиловский журнал генетики и селекции
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Online Access:https://vavilov.elpub.ru/jour/article/view/165
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Summary:New mutants, not described previously, resistant to L-cycloserine and β-chloro-L-alanine were derived from the parental strain Brevibacterium flavum AA5. Their alanine-producing ability was studied. It was found that the resistance to L-cycloserine did not affect the yield of L-alanine significantly, whereas the resistance to β-chloro-L-alanine of B. flavum GL1 and B. flavum GL18 strain-producers exceeds the initial level of L-alanine synthesis by 23 and 38 %, respectively.
ISSN:2500-3259