Male Perineal Carcinoma: Experience in 4 Cases and Literature Review
Perineal carcinoma of unknown origin is a rare and aggressive disease, so an early diagnosis and adequate treatment are essential to prevent its progression. We report the first series of cases of perineal carcinoma of unknown origin: (I) a 62-year-old male patient being followed up for a urethral s...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2022/4466602 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832554771513344000 |
|---|---|
| author | Agustín Fraile Poblador Manuel Hevia Palacios Manuel Rodríguez Vegas Alberto Artiles Medina Enrique Sanz Mayayo Silvia García Barreras Guillermo Fernández Conejo Rafael Rodríguez Patrón Varona Crespo Constatino Ana Saiz González Javier Burgos Revilla |
| author_facet | Agustín Fraile Poblador Manuel Hevia Palacios Manuel Rodríguez Vegas Alberto Artiles Medina Enrique Sanz Mayayo Silvia García Barreras Guillermo Fernández Conejo Rafael Rodríguez Patrón Varona Crespo Constatino Ana Saiz González Javier Burgos Revilla |
| author_sort | Agustín Fraile Poblador |
| collection | DOAJ |
| description | Perineal carcinoma of unknown origin is a rare and aggressive disease, so an early diagnosis and adequate treatment are essential to prevent its progression. We report the first series of cases of perineal carcinoma of unknown origin: (I) a 62-year-old male patient being followed up for a urethral stricture treated with periodic dilations with subsequent development of perineal abscesses and perineal carcinoma; (II) a 67-year-old male patient who consults for urinary discomfort associated with a perineal abscess. Recurrence of the abscess in the first month revealed the presence of an underlying perineal carcinoma; (III) a 78-year-old male patient that underwent urethroplasty with graft with subsequent regimen of periodical dilations. Recurrent formation of perianal abscesses revealed the presence of an underlying perineal carcinoma; and (IV) a 78-year-old male patient with history of in situ penile carcinoma treated by glans resurfacing. He consulted for penile pain, and imaging tests revealed a perineal abscess adjacent to the left corpus cavernosum. The core needle biopsy revealed a squamous cell carcinoma. Penile exploration and negative glans biopsy ruled out possible recurrence of penile carcinoma. The form of presentation of the disease has been very similar in all patients, demonstrating the presence of perineal abscess in all cases. Two patients had inguinal lymph node disease at diagnosis. All patients were treated by surgery, and three of them required adjuvant systemic treatment. Surgery combined with systemic treatment is probably the best option if the patient’s conditions allow it. |
| format | Article |
| id | doaj-art-f26046e03bec482180a64a5eed2ff255 |
| institution | Kabale University |
| issn | 2090-6978 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-f26046e03bec482180a64a5eed2ff2552025-02-03T05:50:38ZengWileyCase Reports in Urology2090-69782022-01-01202210.1155/2022/4466602Male Perineal Carcinoma: Experience in 4 Cases and Literature ReviewAgustín Fraile Poblador0Manuel Hevia Palacios1Manuel Rodríguez Vegas2Alberto Artiles Medina3Enrique Sanz Mayayo4Silvia García Barreras5Guillermo Fernández Conejo6Rafael Rodríguez Patrón7Varona Crespo Constatino8Ana Saiz González9Javier Burgos Revilla10Urology DepartmentUrology DepartmentPlastic Surgery DepartmentUrology DepartmentUrology DepartmentUrology DepartmentUrology DepartmentUrology DepartmentAnatomic Pathology DepartmentAnatomic Pathology DepartmentUrology DepartmentPerineal carcinoma of unknown origin is a rare and aggressive disease, so an early diagnosis and adequate treatment are essential to prevent its progression. We report the first series of cases of perineal carcinoma of unknown origin: (I) a 62-year-old male patient being followed up for a urethral stricture treated with periodic dilations with subsequent development of perineal abscesses and perineal carcinoma; (II) a 67-year-old male patient who consults for urinary discomfort associated with a perineal abscess. Recurrence of the abscess in the first month revealed the presence of an underlying perineal carcinoma; (III) a 78-year-old male patient that underwent urethroplasty with graft with subsequent regimen of periodical dilations. Recurrent formation of perianal abscesses revealed the presence of an underlying perineal carcinoma; and (IV) a 78-year-old male patient with history of in situ penile carcinoma treated by glans resurfacing. He consulted for penile pain, and imaging tests revealed a perineal abscess adjacent to the left corpus cavernosum. The core needle biopsy revealed a squamous cell carcinoma. Penile exploration and negative glans biopsy ruled out possible recurrence of penile carcinoma. The form of presentation of the disease has been very similar in all patients, demonstrating the presence of perineal abscess in all cases. Two patients had inguinal lymph node disease at diagnosis. All patients were treated by surgery, and three of them required adjuvant systemic treatment. Surgery combined with systemic treatment is probably the best option if the patient’s conditions allow it.http://dx.doi.org/10.1155/2022/4466602 |
| spellingShingle | Agustín Fraile Poblador Manuel Hevia Palacios Manuel Rodríguez Vegas Alberto Artiles Medina Enrique Sanz Mayayo Silvia García Barreras Guillermo Fernández Conejo Rafael Rodríguez Patrón Varona Crespo Constatino Ana Saiz González Javier Burgos Revilla Male Perineal Carcinoma: Experience in 4 Cases and Literature Review Case Reports in Urology |
| title | Male Perineal Carcinoma: Experience in 4 Cases and Literature Review |
| title_full | Male Perineal Carcinoma: Experience in 4 Cases and Literature Review |
| title_fullStr | Male Perineal Carcinoma: Experience in 4 Cases and Literature Review |
| title_full_unstemmed | Male Perineal Carcinoma: Experience in 4 Cases and Literature Review |
| title_short | Male Perineal Carcinoma: Experience in 4 Cases and Literature Review |
| title_sort | male perineal carcinoma experience in 4 cases and literature review |
| url | http://dx.doi.org/10.1155/2022/4466602 |
| work_keys_str_mv | AT agustinfrailepoblador maleperinealcarcinomaexperiencein4casesandliteraturereview AT manuelheviapalacios maleperinealcarcinomaexperiencein4casesandliteraturereview AT manuelrodriguezvegas maleperinealcarcinomaexperiencein4casesandliteraturereview AT albertoartilesmedina maleperinealcarcinomaexperiencein4casesandliteraturereview AT enriquesanzmayayo maleperinealcarcinomaexperiencein4casesandliteraturereview AT silviagarciabarreras maleperinealcarcinomaexperiencein4casesandliteraturereview AT guillermofernandezconejo maleperinealcarcinomaexperiencein4casesandliteraturereview AT rafaelrodriguezpatron maleperinealcarcinomaexperiencein4casesandliteraturereview AT varonacrespoconstatino maleperinealcarcinomaexperiencein4casesandliteraturereview AT anasaizgonzalez maleperinealcarcinomaexperiencein4casesandliteraturereview AT javierburgosrevilla maleperinealcarcinomaexperiencein4casesandliteraturereview |