STAG2 expression imparts distinct therapeutic vulnerabilities in muscle-invasive bladder cancer cells

Abstract Expression of stromal antigen 2 (STAG2), a member of the cohesin complex, is associated with aggressive tumor characteristics and worse clinical outcomes in muscle invasive bladder cancer (MIBC) patients. The mechanism by which STAG2 acts in a pro-oncogenic manner in bladder cancer remains...

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Bibliographic Details
Main Authors: Sarah R. Athans, Henry Withers, Aimee Stablewski, Katerina Gurova, Joyce Ohm, Anna Woloszynska
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-025-00548-3
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