Mitochondrial dysfunction and fatigue in Sjögren’s disease

Mitochondrial dysfunction and fatigue in Sjögren’s disease

Objective Sjögren’s disease (SjD) is a chronic exocrine disorder typified by inflammation and dryness, but also profound fatigue, suggesting a pathological basis in cellular bioenergetics. In healthy states, dysfunctional mitochondria are recycled by mitophagic processes; when impaired, poorly funct...

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Main Authors: Astrid Rasmussen, Christopher J Lessard, A Darise Farris, Kristi A Koelsch, Biji T Kurien, Joshua Cavett, Kathy Sivilis, Robert Hal Scofield, John Aubrey Ice, Rebecca A Wood, Gavin Pharaoh, Valerie Lewis, Shylesh Bhaskaran, Holly Van Remmen
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/11/2/e005046.full
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