Multivalent vaccine candidate from conserved immunogenic peptides in entry or exit proteins of Orthopoxvirus genus

Multivalent vaccine candidate from conserved immunogenic peptides in entry or exit proteins of Orthopoxvirus genus

Abstract Orthopoxvirus (OPXV) genus includes emerging and re-emerging zoonotic viruses that pose threats to global health. Smallpox caused pandemics in the 20th century. Borealpox was responsible for a death in Alaska in 2024. Mpox, declared a Public Health Emergency by the WHO in 2022, with an aler...

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Bibliographic Details
Main Authors: Leonardo Pereira de Araújo, Evandro Neves Silva, Severino Matias de Alencar, Patrícia Paiva Corsetti, Leonardo Augusto de Almeida
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Orthopoxvirus
Reverse vaccinology
Multi-epitope
Immunoinformatics
Online Access:https://doi.org/10.1038/s41598-025-96755-4
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