Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 Years

Introduction. This study aimed to evaluate symptoms and signs, inflammation markers, electrolytes, and ECG signs of increased vagal tone as markers of colon perforation in sigmoid diverticulitis or appendicitis. Methods. The records of all patients older than fifty years (only these had routine ECG...

Full description

Saved in:
Bibliographic Details
Main Authors: S. A. Käser, R. Furler, D. C. Evequoz, C. A. Maurer
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2013/462891
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832567002009436160
author S. A. Käser
R. Furler
D. C. Evequoz
C. A. Maurer
author_facet S. A. Käser
R. Furler
D. C. Evequoz
C. A. Maurer
author_sort S. A. Käser
collection DOAJ
description Introduction. This study aimed to evaluate symptoms and signs, inflammation markers, electrolytes, and ECG signs of increased vagal tone as markers of colon perforation in sigmoid diverticulitis or appendicitis. Methods. The records of all patients older than fifty years (only these had routine ECG done) admitted to our emergency station between January 2008 and December 2010 with sigmoid diverticulitis (, diagnosed by computer tomography) or appendicitis (, diagnosed intraoperatively) were retrospectively evaluated. Pain score, heart rate, blood pressure, and body temperature were assessed at presentation. Before starting infusion therapy, blood was taken to do a blood count and to analyze CRP, the electrolytes, and creatinine levels. Then an ECG was done. Results. The perforation rate was 37% (). Body temperature, heart rate, sodium, CRP, and leukocytes correlated significantly with infectious colon perforation. However, only body temperature, CRP, and sodium correlated significantly with infectious colon perforation if compared by logistic regression analysis. The prevalence of hyponatremia (sodium level  mmol/L) was 29% in the group with infectious colon perforation and 16% in the group without (). Conclusion. Hyponatremia is a specific marker of infectious colon perforation in patients older than fifty years.
format Article
id doaj-art-f23ddac324fb4d41afd777d79329bf10
institution Kabale University
issn 1687-6121
1687-630X
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Gastroenterology Research and Practice
spelling doaj-art-f23ddac324fb4d41afd777d79329bf102025-02-03T01:02:43ZengWileyGastroenterology Research and Practice1687-61211687-630X2013-01-01201310.1155/2013/462891462891Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 YearsS. A. Käser0R. Furler1D. C. Evequoz2C. A. Maurer3Department of General, Visceral, Vascular, and Thoracic Surgery, Hospital of Liestal of The University of Basel, Rheinstrasse 26, 4410 Liestal, SwitzerlandDepartment of General, Visceral and Trauma Surgery, Hospital Center of Oberwallis (SZO), Pflanzettastrasse 6, 3930 Visp, SwitzerlandDivision of Cardiology, Department of Internal Medicine, Hospital Center of Oberwallis (SZO), Pflanzettastrasse 6, 3930 Visp, SwitzerlandDepartment of General, Visceral, Vascular, and Thoracic Surgery, Hospital of Liestal of The University of Basel, Rheinstrasse 26, 4410 Liestal, SwitzerlandIntroduction. This study aimed to evaluate symptoms and signs, inflammation markers, electrolytes, and ECG signs of increased vagal tone as markers of colon perforation in sigmoid diverticulitis or appendicitis. Methods. The records of all patients older than fifty years (only these had routine ECG done) admitted to our emergency station between January 2008 and December 2010 with sigmoid diverticulitis (, diagnosed by computer tomography) or appendicitis (, diagnosed intraoperatively) were retrospectively evaluated. Pain score, heart rate, blood pressure, and body temperature were assessed at presentation. Before starting infusion therapy, blood was taken to do a blood count and to analyze CRP, the electrolytes, and creatinine levels. Then an ECG was done. Results. The perforation rate was 37% (). Body temperature, heart rate, sodium, CRP, and leukocytes correlated significantly with infectious colon perforation. However, only body temperature, CRP, and sodium correlated significantly with infectious colon perforation if compared by logistic regression analysis. The prevalence of hyponatremia (sodium level  mmol/L) was 29% in the group with infectious colon perforation and 16% in the group without (). Conclusion. Hyponatremia is a specific marker of infectious colon perforation in patients older than fifty years.http://dx.doi.org/10.1155/2013/462891
spellingShingle S. A. Käser
R. Furler
D. C. Evequoz
C. A. Maurer
Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 Years
Gastroenterology Research and Practice
title Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 Years
title_full Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 Years
title_fullStr Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 Years
title_full_unstemmed Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 Years
title_short Hyponatremia Is a Specific Marker of Perforation in Sigmoid Diverticulitis or Appendicitis in Patients Older Than 50 Years
title_sort hyponatremia is a specific marker of perforation in sigmoid diverticulitis or appendicitis in patients older than 50 years
url http://dx.doi.org/10.1155/2013/462891
work_keys_str_mv AT sakaser hyponatremiaisaspecificmarkerofperforationinsigmoiddiverticulitisorappendicitisinpatientsolderthan50years
AT rfurler hyponatremiaisaspecificmarkerofperforationinsigmoiddiverticulitisorappendicitisinpatientsolderthan50years
AT dcevequoz hyponatremiaisaspecificmarkerofperforationinsigmoiddiverticulitisorappendicitisinpatientsolderthan50years
AT camaurer hyponatremiaisaspecificmarkerofperforationinsigmoiddiverticulitisorappendicitisinpatientsolderthan50years