H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux

H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux

H-NS is a histone-like nucleoid-structuring protein that regulates gene expressions, particularly acquired foreign genes, however, little is known about whether H-NS can modulate bacterial susceptibility by regulating its intrinsic genes. The hns-deleted mutant EΔhns, the hns-complemented strain EΔh...

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Bibliographic Details
Main Authors: Qiuru Chen, Yulei Liang, Yanbin Dong, Junling Cui, Kun He, Xiaoyuan Ma, Jinfeng Zhao, Yajun Zhai, Li Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Veterinary Science
Subjects:
H-NS
aminoglycosides
uptake
efflux
glycolysis
proton motive force
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1534498/full
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