Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and Latency

Vaccine-induced protection is substantial to control, prevent, and reduce the spread of infectious diseases and to get rid of infectious diseases. In this paper, we propose an SVEIR epidemic model with age-dependent vaccination, latency, and infection. The model also considers that the waning vaccin...

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Main Authors: Rodrigue Yves M’pika Massoukou, Suares Clovis Oukouomi Noutchie, Richard Guiem
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Abstract and Applied Analysis
Online Access:http://dx.doi.org/10.1155/2018/8479638
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author Rodrigue Yves M’pika Massoukou
Suares Clovis Oukouomi Noutchie
Richard Guiem
author_facet Rodrigue Yves M’pika Massoukou
Suares Clovis Oukouomi Noutchie
Richard Guiem
author_sort Rodrigue Yves M’pika Massoukou
collection DOAJ
description Vaccine-induced protection is substantial to control, prevent, and reduce the spread of infectious diseases and to get rid of infectious diseases. In this paper, we propose an SVEIR epidemic model with age-dependent vaccination, latency, and infection. The model also considers that the waning vaccine-induced immunity depends on vaccination age and the vaccinated individuals fall back to the susceptible class after losing immunity. The model is a coupled system of (hyperbolic) partial differential equations with ordinary differential equations. The global dynamics of the model is established through construction of appropriate Lyapunov functionals and application of Lasalle’s invariance principle. As a result, the global stability of the infection-free equilibrium and endemic equilibrium is obtained and is fully determined by the basic reproduction number R0.
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institution Kabale University
issn 1085-3375
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series Abstract and Applied Analysis
spelling doaj-art-f2216725995e43c8b8f840690cf18ea22025-02-03T01:10:35ZengWileyAbstract and Applied Analysis1085-33751687-04092018-01-01201810.1155/2018/84796388479638Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and LatencyRodrigue Yves M’pika Massoukou0Suares Clovis Oukouomi Noutchie1Richard Guiem2School of Mathematical and Statistical Sciences, North-West University, Mafikeng campus, Private Bag X2046, Mmabatho 2735, South AfricaSchool of Mathematical and Statistical Sciences, North-West University, Mafikeng campus, Private Bag X2046, Mmabatho 2735, South AfricaSchool of Mathematical and Statistical Sciences, North-West University, Mafikeng campus, Private Bag X2046, Mmabatho 2735, South AfricaVaccine-induced protection is substantial to control, prevent, and reduce the spread of infectious diseases and to get rid of infectious diseases. In this paper, we propose an SVEIR epidemic model with age-dependent vaccination, latency, and infection. The model also considers that the waning vaccine-induced immunity depends on vaccination age and the vaccinated individuals fall back to the susceptible class after losing immunity. The model is a coupled system of (hyperbolic) partial differential equations with ordinary differential equations. The global dynamics of the model is established through construction of appropriate Lyapunov functionals and application of Lasalle’s invariance principle. As a result, the global stability of the infection-free equilibrium and endemic equilibrium is obtained and is fully determined by the basic reproduction number R0.http://dx.doi.org/10.1155/2018/8479638
spellingShingle Rodrigue Yves M’pika Massoukou
Suares Clovis Oukouomi Noutchie
Richard Guiem
Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and Latency
Abstract and Applied Analysis
title Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and Latency
title_full Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and Latency
title_fullStr Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and Latency
title_full_unstemmed Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and Latency
title_short Global Dynamics of an SVEIR Model with Age-Dependent Vaccination, Infection, and Latency
title_sort global dynamics of an sveir model with age dependent vaccination infection and latency
url http://dx.doi.org/10.1155/2018/8479638
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