Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case Presentation

Drug reaction syndrome with eosinophilia and systemic symptoms is a reaction of hypersensitivity which triggers due to multiple drugs such as antibiotics, anti-inflammatory, anti-convulsants which occur in 2,2 % of admitted patients. Its importance is related in the high mortality that can achieve 3...

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Main Authors: Omar Rangel Betarte, Mileny Acosta Fonseca, Vanessa Flores Hernández
Format: Article
Language:Spanish
Published: Universidad de las Ciencias Médicas de Cienfuegos 2019-02-01
Series:Revista Finlay
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Online Access:https://revfinlay.sld.cu/index.php/finlay/article/view/678
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author Omar Rangel Betarte
Mileny Acosta Fonseca
Vanessa Flores Hernández
author_facet Omar Rangel Betarte
Mileny Acosta Fonseca
Vanessa Flores Hernández
author_sort Omar Rangel Betarte
collection DOAJ
description Drug reaction syndrome with eosinophilia and systemic symptoms is a reaction of hypersensitivity which triggers due to multiple drugs such as antibiotics, anti-inflammatory, anti-convulsants which occur in 2,2 % of admitted patients. Its importance is related in the high mortality that can achieve 30 %. A case of a 5 year old boy with antecedents of diagnosed epilepsy, treated with carbamazepine, who short time after starting the treatment had fever for 11 days. Posteriorly cutaneous erythematous pruritic maculopapular skin lesions appeared. He was admitted with the diagnosis of prolonged febrile syndrome. Laboratory test showed eosinophilia, elevation of liver tests and C-reactive protein. A syndrome of drug sensitivity was considered induced by carbamazepine, after the result of skin biopsy anti-comicial is suspended thus improving the condition, with normalization of eosinophils and liver function. The patient progressed without fever and good general condition. The case is presented due to the low prevalence of this syndrome in the University Pediatric Hospital Paquito González Cueto. Cienfuegos.
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spelling doaj-art-f218af204e324b2ba1f60e1de19bbe912025-01-30T21:21:59ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342019-02-01916368398Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case PresentationOmar Rangel Betarte0Mileny Acosta Fonseca1Vanessa Flores Hernández2Hospital Pediátrico Universitario Paquito González Cueto. Cienfuegos.Hospital Pediátrico Universitario Paquito González Cueto. Cienfuegos.Hospital Pediátrico Universitario Paquito González Cueto. Cienfuegos.Drug reaction syndrome with eosinophilia and systemic symptoms is a reaction of hypersensitivity which triggers due to multiple drugs such as antibiotics, anti-inflammatory, anti-convulsants which occur in 2,2 % of admitted patients. Its importance is related in the high mortality that can achieve 30 %. A case of a 5 year old boy with antecedents of diagnosed epilepsy, treated with carbamazepine, who short time after starting the treatment had fever for 11 days. Posteriorly cutaneous erythematous pruritic maculopapular skin lesions appeared. He was admitted with the diagnosis of prolonged febrile syndrome. Laboratory test showed eosinophilia, elevation of liver tests and C-reactive protein. A syndrome of drug sensitivity was considered induced by carbamazepine, after the result of skin biopsy anti-comicial is suspended thus improving the condition, with normalization of eosinophils and liver function. The patient progressed without fever and good general condition. The case is presented due to the low prevalence of this syndrome in the University Pediatric Hospital Paquito González Cueto. Cienfuegos.https://revfinlay.sld.cu/index.php/finlay/article/view/678síndrome de hipersensibilidad a medicamentoseosinofiliainformes de casos
spellingShingle Omar Rangel Betarte
Mileny Acosta Fonseca
Vanessa Flores Hernández
Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case Presentation
Revista Finlay
síndrome de hipersensibilidad a medicamentos
eosinofilia
informes de casos
title Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case Presentation
title_full Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case Presentation
title_fullStr Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case Presentation
title_full_unstemmed Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case Presentation
title_short Drug Reaction Syndrome with Eosinophilia and Systemic Symptoms. Case Presentation
title_sort drug reaction syndrome with eosinophilia and systemic symptoms case presentation
topic síndrome de hipersensibilidad a medicamentos
eosinofilia
informes de casos
url https://revfinlay.sld.cu/index.php/finlay/article/view/678
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AT milenyacostafonseca drugreactionsyndromewitheosinophiliaandsystemicsymptomscasepresentation
AT vanessafloreshernandez drugreactionsyndromewitheosinophiliaandsystemicsymptomscasepresentation