SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTS
ABSTRACT BACKGROUND: Gastric stump neoplasia is defined as a neoplasia that arises in the gastric remnant after at least 5 years of interval from the first gastric resection. AIMS: The aim of this study was to analyze 51 patients who underwent total and subtotal gastrectomy and multi-visceral rese...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Colégio Brasileiro de Cirurgia Digestiva
2025-01-01
|
| Series: | ABCD: Arquivos Brasileiros de Cirurgia Digestiva |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100333&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832592540971302912 |
|---|---|
| author | Eric DRIZLIONOKS Valdir TERCIOTI JUNIOR João de Souza COELHO NETO Nelson Adami ANDREOLLO Luiz Roberto LOPES |
| author_facet | Eric DRIZLIONOKS Valdir TERCIOTI JUNIOR João de Souza COELHO NETO Nelson Adami ANDREOLLO Luiz Roberto LOPES |
| author_sort | Eric DRIZLIONOKS |
| collection | DOAJ |
| description | ABSTRACT BACKGROUND: Gastric stump neoplasia is defined as a neoplasia that arises in the gastric remnant after at least 5 years of interval from the first gastric resection. AIMS: The aim of this study was to analyze 51 patients who underwent total and subtotal gastrectomy and multi-visceral resections in patients with gastric stump cancer. METHODS: The hospital records of 51 patients surgically treated for gastric stump cancer between 1989 and 2019 were reviewed. The following data were analyzed: sex, age group, the interval between the first surgery and the diagnosis of gastric stump cancer, location of the ulcer that motivated the gastrectomy, type of reconstruction, tumor resectability, surgery performed, reconstruction of the digestive tract, associated surgical procedures, postoperative complications using the Clavien-Dindo classification, disease staging, and survival. RESULTS: There were 43 (83.3%) men, with a mean age of 66.9 years. The mean interval between the initial gastrectomy and surgery for the treatment of gastric stump neoplasia was 34.7 years. All had previously undergone Billroth II reconstruction. Most patients underwent total gastrectomy (35 cases – 68.6%), followed by subtotal gastrectomy (6 cases – 11.8%), and the remainder were considered unresectable (10 patients – 19.6%), undergoing jejunostomy for nutritional support. Multi-visceral resections consisted of splenectomies, cholecystectomies, hepatectomies, partial colectomies, pancreatectomies, enterectomies, and nephrectomies. Among the patients who had the lesion resected, the mean follow-up time was 34.2 months (standard deviation: 47.6 months), the overall survival at 3 years was 43.6%, and the survival at 5 years was 29.7%. CONCLUSION: The treatment of gastric stump neoplasia is still challenging and difficult, and personalized follow-up strategies should be focused on high-risk patients, offering opportunities for early intervention, better clinical outcomes, and long-term survival. |
| format | Article |
| id | doaj-art-f1fb5b18ab5b429694c82b5eb114239d |
| institution | Kabale University |
| issn | 0102-6720 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Colégio Brasileiro de Cirurgia Digestiva |
| record_format | Article |
| series | ABCD: Arquivos Brasileiros de Cirurgia Digestiva |
| spelling | doaj-art-f1fb5b18ab5b429694c82b5eb114239d2025-01-21T07:40:21ZengColégio Brasileiro de Cirurgia DigestivaABCD: Arquivos Brasileiros de Cirurgia Digestiva0102-67202025-01-013710.1590/0102-6720202400056e1850SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTSEric DRIZLIONOKShttps://orcid.org/0000-0001-7176-0670Valdir TERCIOTI JUNIORhttps://orcid.org/0000-0003-0510-7360João de Souza COELHO NETOhttps://orcid.org/0000-0001-7415-1635Nelson Adami ANDREOLLOhttps://orcid.org/0000-0001-7452-1165Luiz Roberto LOPEShttps://orcid.org/0000-0002-8996-6658ABSTRACT BACKGROUND: Gastric stump neoplasia is defined as a neoplasia that arises in the gastric remnant after at least 5 years of interval from the first gastric resection. AIMS: The aim of this study was to analyze 51 patients who underwent total and subtotal gastrectomy and multi-visceral resections in patients with gastric stump cancer. METHODS: The hospital records of 51 patients surgically treated for gastric stump cancer between 1989 and 2019 were reviewed. The following data were analyzed: sex, age group, the interval between the first surgery and the diagnosis of gastric stump cancer, location of the ulcer that motivated the gastrectomy, type of reconstruction, tumor resectability, surgery performed, reconstruction of the digestive tract, associated surgical procedures, postoperative complications using the Clavien-Dindo classification, disease staging, and survival. RESULTS: There were 43 (83.3%) men, with a mean age of 66.9 years. The mean interval between the initial gastrectomy and surgery for the treatment of gastric stump neoplasia was 34.7 years. All had previously undergone Billroth II reconstruction. Most patients underwent total gastrectomy (35 cases – 68.6%), followed by subtotal gastrectomy (6 cases – 11.8%), and the remainder were considered unresectable (10 patients – 19.6%), undergoing jejunostomy for nutritional support. Multi-visceral resections consisted of splenectomies, cholecystectomies, hepatectomies, partial colectomies, pancreatectomies, enterectomies, and nephrectomies. Among the patients who had the lesion resected, the mean follow-up time was 34.2 months (standard deviation: 47.6 months), the overall survival at 3 years was 43.6%, and the survival at 5 years was 29.7%. CONCLUSION: The treatment of gastric stump neoplasia is still challenging and difficult, and personalized follow-up strategies should be focused on high-risk patients, offering opportunities for early intervention, better clinical outcomes, and long-term survival.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100333&lng=en&tlng=enGastric stumpStomach neoplasmsGastrectomyPostoperative complicationsSurvival |
| spellingShingle | Eric DRIZLIONOKS Valdir TERCIOTI JUNIOR João de Souza COELHO NETO Nelson Adami ANDREOLLO Luiz Roberto LOPES SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTS ABCD: Arquivos Brasileiros de Cirurgia Digestiva Gastric stump Stomach neoplasms Gastrectomy Postoperative complications Survival |
| title | SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTS |
| title_full | SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTS |
| title_fullStr | SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTS |
| title_full_unstemmed | SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTS |
| title_short | SURGICAL TREATMENT OF GASTRIC STUMP CANCER: A COHORT STUDY OF 51 PATIENTS |
| title_sort | surgical treatment of gastric stump cancer a cohort study of 51 patients |
| topic | Gastric stump Stomach neoplasms Gastrectomy Postoperative complications Survival |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100333&lng=en&tlng=en |
| work_keys_str_mv | AT ericdrizlionoks surgicaltreatmentofgastricstumpcanceracohortstudyof51patients AT valdirterciotijunior surgicaltreatmentofgastricstumpcanceracohortstudyof51patients AT joaodesouzacoelhoneto surgicaltreatmentofgastricstumpcanceracohortstudyof51patients AT nelsonadamiandreollo surgicaltreatmentofgastricstumpcanceracohortstudyof51patients AT luizrobertolopes surgicaltreatmentofgastricstumpcanceracohortstudyof51patients |