Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis

Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis

Background Groundbreaking studies have linked the gut microbiome with immune homeostasis and antitumor immune responses. Mounting evidence has also demonstrated an intratumoral microbiome, including in soft tissue sarcomas (STS), although detailed characterization of the STS intratumoral microbiome...

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Main Authors: William J Murphy, Robert J Canter, Nikhil Joshi, Sean J Judge, Morgan A Darrow, Steve W Thorpe, Alicia A Gingrich, Lauren M Perry, Sylvia M Cruz, Kara T Kleber, Louis B Jones, Ugur N Basmaci, Matthew L Settles, Blythe P Durbin-Johnson, Arta Monir Monjazeb, Janai Carr-Ascher, Jonathan A Eisen
Format: Article
Language:English
Published: BMJ Publishing Group 2023-01-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/1/e004285.full
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