Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol

Background: While the prevalence of inflammatory bowel disease (IBD) is rising globally, there is limited knowledge regarding its activity status and associated factors, especially in Guilan Province, Iran. Objectives: This protocol outlines a case-control study aiming to assess the activity status...

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Main Authors: Mehrnaz Asgharnezhad, Ehsan Amini-Salehi, Niloofar Faraji, Soheil Hassanipour, Saman Maroufizadeh, Adele Isanazar, Marjan Mahdavi-Roshan, Zahra Hedayatzadeh, Farahnaz Joukar, Fariborz Mansour Ghanaei
Format: Article
Language:English
Published: Guilan University of Medical Sciences 2025-01-01
Series:Caspian Journal of Health Research
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Online Access:http://cjhr.gums.ac.ir/article-1-391-en.pdf
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author Mehrnaz Asgharnezhad
Ehsan Amini-Salehi
Niloofar Faraji
Soheil Hassanipour
Saman Maroufizadeh
Adele Isanazar
Marjan Mahdavi-Roshan
Zahra Hedayatzadeh
Farahnaz Joukar
Fariborz Mansour Ghanaei
author_facet Mehrnaz Asgharnezhad
Ehsan Amini-Salehi
Niloofar Faraji
Soheil Hassanipour
Saman Maroufizadeh
Adele Isanazar
Marjan Mahdavi-Roshan
Zahra Hedayatzadeh
Farahnaz Joukar
Fariborz Mansour Ghanaei
author_sort Mehrnaz Asgharnezhad
collection DOAJ
description Background: While the prevalence of inflammatory bowel disease (IBD) is rising globally, there is limited knowledge regarding its activity status and associated factors, especially in Guilan Province, Iran. Objectives: This protocol outlines a case-control study aiming to assess the activity status of IBD and explore its related factors in the region. Materials & Methods: The study will utilize a case-control design of patients with IBD. Cases will consist of individuals with active IBD, while controls will be selected from those with inactive diseases. The selection of participants will be based on predefined criteria and matched for age and gender. A comprehensive set of variables will be examined, including demographic characteristics, nutritional status, lifestyle factors, medical history, and disease-related factors. Standardized questionnaires will gather information on disease activity, symptomatology, lifestyle behaviors, and nutritional status. Statistical analyses will be conducted to evaluate the association between disease activity status and the identified factors. Regression models will be employed to control for potential confounders and assess the independent effects of each variable. Conclusion: The findings from this study are expected to provide valuable insights into the activity status of IBD and its related factors in Guilan Province, Iran. By examining a range of variables, the study aims to enhance our understanding of the disease activity and identify potential modifiable risk factors. The results may have implications for improved management strategies with IBD in this region.
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publisher Guilan University of Medical Sciences
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spelling doaj-art-f1b8cb51ad614bcfbe3fc93796634eb52025-02-06T07:54:06ZengGuilan University of Medical SciencesCaspian Journal of Health Research2423-81712025-01-011015562Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study ProtocolMehrnaz Asgharnezhad0Ehsan Amini-Salehi1Niloofar Faraji2Soheil Hassanipour3Saman Maroufizadeh4Adele Isanazar5Marjan Mahdavi-Roshan6Zahra Hedayatzadeh7Farahnaz Joukar8Fariborz Mansour Ghanaei9 Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Department of Biostatistics and Epidemiology, Faculty of Health, Guilan University of Medical Sciences, Rasht, Iran. Kavosh Cognitive Behavior Sciences and Addiction Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran. Department of Cardiology, Cardiovascular Disease Research Center, Faculty of Medicine, Heshmat Hospital, Guilan University of Medical Sciences, Rasht, Iran. Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Background: While the prevalence of inflammatory bowel disease (IBD) is rising globally, there is limited knowledge regarding its activity status and associated factors, especially in Guilan Province, Iran. Objectives: This protocol outlines a case-control study aiming to assess the activity status of IBD and explore its related factors in the region. Materials & Methods: The study will utilize a case-control design of patients with IBD. Cases will consist of individuals with active IBD, while controls will be selected from those with inactive diseases. The selection of participants will be based on predefined criteria and matched for age and gender. A comprehensive set of variables will be examined, including demographic characteristics, nutritional status, lifestyle factors, medical history, and disease-related factors. Standardized questionnaires will gather information on disease activity, symptomatology, lifestyle behaviors, and nutritional status. Statistical analyses will be conducted to evaluate the association between disease activity status and the identified factors. Regression models will be employed to control for potential confounders and assess the independent effects of each variable. Conclusion: The findings from this study are expected to provide valuable insights into the activity status of IBD and its related factors in Guilan Province, Iran. By examining a range of variables, the study aims to enhance our understanding of the disease activity and identify potential modifiable risk factors. The results may have implications for improved management strategies with IBD in this region.http://cjhr.gums.ac.ir/article-1-391-en.pdfcrohn’s disease (cd)ulcerative colitis (uc)inflammatory bowel disease (ibd)iranepidemiology
spellingShingle Mehrnaz Asgharnezhad
Ehsan Amini-Salehi
Niloofar Faraji
Soheil Hassanipour
Saman Maroufizadeh
Adele Isanazar
Marjan Mahdavi-Roshan
Zahra Hedayatzadeh
Farahnaz Joukar
Fariborz Mansour Ghanaei
Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol
Caspian Journal of Health Research
crohn’s disease (cd)
ulcerative colitis (uc)
inflammatory bowel disease (ibd)
iran
epidemiology
title Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol
title_full Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol
title_fullStr Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol
title_full_unstemmed Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol
title_short Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol
title_sort investigating the activity status of inflammatory bowel disease and its related factors a study protocol
topic crohn’s disease (cd)
ulcerative colitis (uc)
inflammatory bowel disease (ibd)
iran
epidemiology
url http://cjhr.gums.ac.ir/article-1-391-en.pdf
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