Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis
BACKGROUND: Depression complicates interferon-based hepatitis C virus (HCV) antiviral therapy in 10% to 40% of cases, and diminishes patient well-being and ability to complete a full course of therapy. As a consequence, the likelihood of achieving a sustained virological response (SVR [ie, permanent...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2013/832689 |
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| _version_ | 1832549207608655872 |
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| author | Awad Al-Omari Juthaporn Cowan Lucy Turner Curtis Cooper |
| author_facet | Awad Al-Omari Juthaporn Cowan Lucy Turner Curtis Cooper |
| author_sort | Awad Al-Omari |
| collection | DOAJ |
| description | BACKGROUND: Depression complicates interferon-based hepatitis C virus (HCV) antiviral therapy in 10% to 40% of cases, and diminishes patient well-being and ability to complete a full course of therapy. As a consequence, the likelihood of achieving a sustained virological response (SVR [ie, permanent viral eradication]) is reduced. |
| format | Article |
| id | doaj-art-f19bb30f90d24d3c8d99ff9786165397 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-f19bb30f90d24d3c8d99ff97861653972025-02-03T06:11:58ZengWileyCanadian Journal of Gastroenterology0835-79002013-01-01271057558110.1155/2013/832689Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-AnalysisAwad Al-Omari0Juthaporn Cowan1Lucy Turner2Curtis Cooper3University of Ottawa, Division of Infectious Diseases, Ottawa, Ontario, CanadaUniversity of Ottawa, Division of Infectious Diseases, Ottawa, Ontario, CanadaOttawa Hospital Research Institute, Ottawa, Ontario, CanadaUniversity of Ottawa, Division of Infectious Diseases, Ottawa, Ontario, CanadaBACKGROUND: Depression complicates interferon-based hepatitis C virus (HCV) antiviral therapy in 10% to 40% of cases, and diminishes patient well-being and ability to complete a full course of therapy. As a consequence, the likelihood of achieving a sustained virological response (SVR [ie, permanent viral eradication]) is reduced.http://dx.doi.org/10.1155/2013/832689 |
| spellingShingle | Awad Al-Omari Juthaporn Cowan Lucy Turner Curtis Cooper Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis Canadian Journal of Gastroenterology |
| title | Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis |
| title_full | Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis |
| title_fullStr | Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis |
| title_short | Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis |
| title_sort | antidepressant prophylaxis reduces depression risk but does not improve sustained virological response in hepatitis c patients receiving interferon without depression at baseline a systematic review and meta analysis |
| url | http://dx.doi.org/10.1155/2013/832689 |
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