The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP

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Main Authors: Jonathan D. Douros, Jonathan N. Flak, Patrick J. Knerr
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1530985/full
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author Jonathan D. Douros
Jonathan N. Flak
Jonathan N. Flak
Patrick J. Knerr
author_facet Jonathan D. Douros
Jonathan N. Flak
Jonathan N. Flak
Patrick J. Knerr
author_sort Jonathan D. Douros
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institution Kabale University
issn 1664-2392
language English
publishDate 2025-02-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Endocrinology
spelling doaj-art-f190853599a54475b970f2fda7d06e4e2025-02-03T05:11:59ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-02-011610.3389/fendo.2025.15309851530985The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIPJonathan D. Douros0Jonathan N. Flak1Jonathan N. Flak2Patrick J. Knerr3Indiana Biosciences Research Institute, Indianapolis, IN, United StatesIndiana Biosciences Research Institute, Indianapolis, IN, United StatesDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, United StatesIndiana Biosciences Research Institute, Indianapolis, IN, United Stateshttps://www.frontiersin.org/articles/10.3389/fendo.2025.1530985/fullGLP-1 - glucagon-like peptide-1GIP - glucose-dependent insulinotropic peptideobesityincretinpharmacology
spellingShingle Jonathan D. Douros
Jonathan N. Flak
Jonathan N. Flak
Patrick J. Knerr
The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP
Frontiers in Endocrinology
GLP-1 - glucagon-like peptide-1
GIP - glucose-dependent insulinotropic peptide
obesity
incretin
pharmacology
title The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP
title_full The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP
title_fullStr The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP
title_full_unstemmed The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP
title_short The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP
title_sort agony and the efficacy central mechanisms of glp 1 induced adverse events and their mitigation by gip
topic GLP-1 - glucagon-like peptide-1
GIP - glucose-dependent insulinotropic peptide
obesity
incretin
pharmacology
url https://www.frontiersin.org/articles/10.3389/fendo.2025.1530985/full
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