Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum)
Anthralin is medically and chemically an important compound which can be found in rhubarb roots. Anthralin and anthralin derivatives have been used as antipsoriatic drugs. In this research, pure anthralin was isolated from the rhubarb roots by maceration and Soxhlet extraction methods in various pol...
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2007/620396 |
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| author | A. Ashnagar N. Gharib Naseri H. Haidari Nasab |
| author_facet | A. Ashnagar N. Gharib Naseri H. Haidari Nasab |
| author_sort | A. Ashnagar |
| collection | DOAJ |
| description | Anthralin is medically and chemically an important compound which can be found in rhubarb roots. Anthralin and anthralin derivatives have been used as antipsoriatic drugs. In this research, pure anthralin was isolated from the rhubarb roots by maceration and Soxhlet extraction methods in various polar and non-polar solvents. Successive TLC and column chromatography on silica gel with chloroform as the mobile phase afforded two distinct fractions with Rf= 0.54 and 0.61. The 1HNMR, 13CNMR, IR, UV and MS spectra showed that the fraction with Rf= 0.61 was anthralin. In both methods, methanol was found to be the most suitable solvent for extraction. |
| format | Article |
| id | doaj-art-f1887498030e41938e974b40a4b65b32 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-f1887498030e41938e974b40a4b65b322025-02-03T01:02:40ZengWileyE-Journal of Chemistry0973-49452090-98102007-01-014454654910.1155/2007/620396Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum)A. Ashnagar0N. Gharib Naseri1H. Haidari Nasab2School of Pharmacy, Ahwaz Jundi Shapour Univ. of Medical Sciences, Ahwaz, IranAhwaz Faculty of Petroleum Engineering, Petroleum Univ. of Technology, IranSchool of Pharmacy, Ahwaz Jundi Shapour Univ. of Medical Sciences, Ahwaz, IranAnthralin is medically and chemically an important compound which can be found in rhubarb roots. Anthralin and anthralin derivatives have been used as antipsoriatic drugs. In this research, pure anthralin was isolated from the rhubarb roots by maceration and Soxhlet extraction methods in various polar and non-polar solvents. Successive TLC and column chromatography on silica gel with chloroform as the mobile phase afforded two distinct fractions with Rf= 0.54 and 0.61. The 1HNMR, 13CNMR, IR, UV and MS spectra showed that the fraction with Rf= 0.61 was anthralin. In both methods, methanol was found to be the most suitable solvent for extraction.http://dx.doi.org/10.1155/2007/620396 |
| spellingShingle | A. Ashnagar N. Gharib Naseri H. Haidari Nasab Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum) E-Journal of Chemistry |
| title | Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum) |
| title_full | Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum) |
| title_fullStr | Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum) |
| title_full_unstemmed | Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum) |
| title_short | Isolation and Identification of Anthralin From the Roots of Rhubarb Plant (Rheum palmatum) |
| title_sort | isolation and identification of anthralin from the roots of rhubarb plant rheum palmatum |
| url | http://dx.doi.org/10.1155/2007/620396 |
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