Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation
The rare occurrence of diffuse large B-cell lymphoma (DLBCL) limited to the spleen presents difficulties in diagnosis. A case report details a patient whose initial symptoms were neck and shoulder pain, subsequently diagnosed as spontaneous spleen rupture, a rare complication of primary splenic lymp...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1449966/full |
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| author | Shifu Hu Yuanyuan Hao Xiangyu Liu Hanbo Liu |
| author_facet | Shifu Hu Yuanyuan Hao Xiangyu Liu Hanbo Liu |
| author_sort | Shifu Hu |
| collection | DOAJ |
| description | The rare occurrence of diffuse large B-cell lymphoma (DLBCL) limited to the spleen presents difficulties in diagnosis. A case report details a patient whose initial symptoms were neck and shoulder pain, subsequently diagnosed as spontaneous spleen rupture, a rare complication of primary splenic lymphoma. Following a splenectomy, the patient was confirmed to have primary splenic DLBCL and made a good postoperative recovery. This report highlights the diagnostic dilemmas in atypical presentations, where neck and shoulder pain may be the only early sign of a neglected spleen rupture, lacking typical symptoms of the underlying disease. In cases of patients who are not stable, the recommended first imaging method is a focused assessment using sonography for trauma (FAST), as CT scans have a high level of sensitivity. Treatment is determined by hemodynamic status, with conservative management for stable patients and surgical intervention for unstable patients. The importance of recognizing spontaneous spleen rupture as a critical yet uncommon possibility in acute abdominal cases, especially in instances of primary splenic DLBCL, is emphasized in the report. |
| format | Article |
| id | doaj-art-f181770c06e5493cb9421b259784829e |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-f181770c06e5493cb9421b259784829e2025-02-04T05:27:56ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-02-011510.3389/fonc.2025.14499661449966Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentationShifu Hu0Yuanyuan Hao1Xiangyu Liu2Hanbo Liu3Department of General Surgery, Tianjin Xiqing Hospital, Tianjin, ChinaDepartment of Geriatrics, Tianjin Xiqing Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Xiqing Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Xiqing Hospital, Tianjin, ChinaThe rare occurrence of diffuse large B-cell lymphoma (DLBCL) limited to the spleen presents difficulties in diagnosis. A case report details a patient whose initial symptoms were neck and shoulder pain, subsequently diagnosed as spontaneous spleen rupture, a rare complication of primary splenic lymphoma. Following a splenectomy, the patient was confirmed to have primary splenic DLBCL and made a good postoperative recovery. This report highlights the diagnostic dilemmas in atypical presentations, where neck and shoulder pain may be the only early sign of a neglected spleen rupture, lacking typical symptoms of the underlying disease. In cases of patients who are not stable, the recommended first imaging method is a focused assessment using sonography for trauma (FAST), as CT scans have a high level of sensitivity. Treatment is determined by hemodynamic status, with conservative management for stable patients and surgical intervention for unstable patients. The importance of recognizing spontaneous spleen rupture as a critical yet uncommon possibility in acute abdominal cases, especially in instances of primary splenic DLBCL, is emphasized in the report.https://www.frontiersin.org/articles/10.3389/fonc.2025.1449966/fullspontaneous splenic ruptureprimary splenic diffuse large B-cell lymphomasplenectomyKehr’s signcase report |
| spellingShingle | Shifu Hu Yuanyuan Hao Xiangyu Liu Hanbo Liu Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation Frontiers in Oncology spontaneous splenic rupture primary splenic diffuse large B-cell lymphoma splenectomy Kehr’s sign case report |
| title | Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation |
| title_full | Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation |
| title_fullStr | Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation |
| title_full_unstemmed | Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation |
| title_short | Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation |
| title_sort | unusual symptoms reveal a rare splenic lymphoma a case report of ps dlbcl with neck and shoulder pain as the initial presentation |
| topic | spontaneous splenic rupture primary splenic diffuse large B-cell lymphoma splenectomy Kehr’s sign case report |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1449966/full |
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