DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway

DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway

Abstract Background Ovarian cancer (OC) remains a lethal gynecological malignancy with an alarming mortality rate, primarily attributed to delayed diagnosis and a lack of effective treatment modalities. Accumulated evidence highlights the pivotal role of reprogrammed lipid metabolism in fueling OC p...

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Bibliographic Details
Main Authors: Hui Wang, Shen Luo, Yue Yin, Yang Liu, Xiaomei Sun, Ling Qiu, Xin Wu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer Cell International
Subjects:
Ovarian cancer
DLAT
Lipid metabolism
SREBP1
JAK2/STAT5 signaling
Online Access:https://doi.org/10.1186/s12935-025-03656-7
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