Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity
Nasopharyngeal carcinoma is an endemic entity with a strong association with Epstein-Barr virus and a new recognition of human papilloma virus-mediated effects in nonendemic areas. Here, we discuss a nasopharyngeal carcinoma suspected as based on imaging results with metastasis to the lymph nodes, l...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2024/8881912 |
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| _version_ | 1832546236568174592 |
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| author | Thomas Auen Geoffrey Talmon |
| author_facet | Thomas Auen Geoffrey Talmon |
| author_sort | Thomas Auen |
| collection | DOAJ |
| description | Nasopharyngeal carcinoma is an endemic entity with a strong association with Epstein-Barr virus and a new recognition of human papilloma virus-mediated effects in nonendemic areas. Here, we discuss a nasopharyngeal carcinoma suspected as based on imaging results with metastasis to the lymph nodes, lung, spleen, bone, and liver. Gross and microscopic findings from the autopsy were clinicopathologically correlated with antemortem clinical studies and investigations. The authors report a case of EBV- and HPV-negative nonendemic, multisite metastatic nasopharyngeal carcinoma, shown to be nonkeratinizing undifferentiated subtype. |
| format | Article |
| id | doaj-art-f138c76ff55e4ae5b33c11d71aac50fa |
| institution | Kabale University |
| issn | 2090-679X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-f138c76ff55e4ae5b33c11d71aac50fa2025-02-03T07:23:39ZengWileyCase Reports in Pathology2090-679X2024-01-01202410.1155/2024/8881912Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV NegativityThomas Auen0Geoffrey Talmon1University of Nebraska Medical CenterUniversity of Nebraska Medical CenterNasopharyngeal carcinoma is an endemic entity with a strong association with Epstein-Barr virus and a new recognition of human papilloma virus-mediated effects in nonendemic areas. Here, we discuss a nasopharyngeal carcinoma suspected as based on imaging results with metastasis to the lymph nodes, lung, spleen, bone, and liver. Gross and microscopic findings from the autopsy were clinicopathologically correlated with antemortem clinical studies and investigations. The authors report a case of EBV- and HPV-negative nonendemic, multisite metastatic nasopharyngeal carcinoma, shown to be nonkeratinizing undifferentiated subtype.http://dx.doi.org/10.1155/2024/8881912 |
| spellingShingle | Thomas Auen Geoffrey Talmon Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity Case Reports in Pathology |
| title | Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity |
| title_full | Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity |
| title_fullStr | Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity |
| title_full_unstemmed | Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity |
| title_short | Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity |
| title_sort | nasopharyngeal carcinoma connecting antemortem and postmortem findings to highlight a rare case of ebv and hpv negativity |
| url | http://dx.doi.org/10.1155/2024/8881912 |
| work_keys_str_mv | AT thomasauen nasopharyngealcarcinomaconnectingantemortemandpostmortemfindingstohighlightararecaseofebvandhpvnegativity AT geoffreytalmon nasopharyngealcarcinomaconnectingantemortemandpostmortemfindingstohighlightararecaseofebvandhpvnegativity |