Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae)
Abstract Background Culex pipiens is one of the most important mosquito transmitter of diseases that attains its greatest impact as a vector through spreading out several serious arboviral, protozoal and filarial diseases. Furthermore, it is a native in Europe, Asia and Africa. Results The current s...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-01-01
|
| Series: | Journal of Basic and Applied Zoology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41936-024-00420-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832594520484610048 |
|---|---|
| author | Alaa Fouaad Nagwa A. Rashdan Refaat M. Gabre Emtithal M. Abdel-Samie |
| author_facet | Alaa Fouaad Nagwa A. Rashdan Refaat M. Gabre Emtithal M. Abdel-Samie |
| author_sort | Alaa Fouaad |
| collection | DOAJ |
| description | Abstract Background Culex pipiens is one of the most important mosquito transmitter of diseases that attains its greatest impact as a vector through spreading out several serious arboviral, protozoal and filarial diseases. Furthermore, it is a native in Europe, Asia and Africa. Results The current study aimed to find a new mosquito biocontrol agents through using the isolated endogenous midgut microbiota, Atlantibacter hermannii, Klebsiella sp. and Enterobacter cloacae, that were isolated from Culex pipiens complex females’ gut. The genotoxical effect of the isolated bacteria was estimated through using alkaline comet assay and related to the impact on mosquito longevity and reproductive potential that might be observed. A distinguish increase in cell DNA damage accompanied with an outstanding effect on life span and reproductive fitness was clear in case of vectors under investigation. Conclusions Data in this research suggest the use of the endogenous bacteria as a potential control techniques that could be integrated in to the environmentally friendly mosquito control strategies. |
| format | Article |
| id | doaj-art-f10c2972b3e94c7599f7973000fd1995 |
| institution | Kabale University |
| issn | 2090-990X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Journal of Basic and Applied Zoology |
| spelling | doaj-art-f10c2972b3e94c7599f7973000fd19952025-01-19T12:34:01ZengSpringerOpenJournal of Basic and Applied Zoology2090-990X2025-01-0186111110.1186/s41936-024-00420-7Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae)Alaa Fouaad0Nagwa A. Rashdan1Refaat M. Gabre2Emtithal M. Abdel-Samie3Entomology Department, Faculty of Science, Cairo UniversityEntomology Department, Faculty of Science, Cairo UniversityBiotechnology Department, Faculty of Science, Cairo UniversityEntomology Department, Faculty of Science, Cairo UniversityAbstract Background Culex pipiens is one of the most important mosquito transmitter of diseases that attains its greatest impact as a vector through spreading out several serious arboviral, protozoal and filarial diseases. Furthermore, it is a native in Europe, Asia and Africa. Results The current study aimed to find a new mosquito biocontrol agents through using the isolated endogenous midgut microbiota, Atlantibacter hermannii, Klebsiella sp. and Enterobacter cloacae, that were isolated from Culex pipiens complex females’ gut. The genotoxical effect of the isolated bacteria was estimated through using alkaline comet assay and related to the impact on mosquito longevity and reproductive potential that might be observed. A distinguish increase in cell DNA damage accompanied with an outstanding effect on life span and reproductive fitness was clear in case of vectors under investigation. Conclusions Data in this research suggest the use of the endogenous bacteria as a potential control techniques that could be integrated in to the environmentally friendly mosquito control strategies.https://doi.org/10.1186/s41936-024-00420-7Culex pipiensMidgut bacteriaReproductive capacityComet assay |
| spellingShingle | Alaa Fouaad Nagwa A. Rashdan Refaat M. Gabre Emtithal M. Abdel-Samie Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae) Journal of Basic and Applied Zoology Culex pipiens Midgut bacteria Reproductive capacity Comet assay |
| title | Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae) |
| title_full | Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae) |
| title_fullStr | Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae) |
| title_full_unstemmed | Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae) |
| title_short | Implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of Culex pipiens complex (Diptera: Culicidae) |
| title_sort | implication of the endogenous midgut microbiota on cell genotoxicity and biological fitness of culex pipiens complex diptera culicidae |
| topic | Culex pipiens Midgut bacteria Reproductive capacity Comet assay |
| url | https://doi.org/10.1186/s41936-024-00420-7 |
| work_keys_str_mv | AT alaafouaad implicationoftheendogenousmidgutmicrobiotaoncellgenotoxicityandbiologicalfitnessofculexpipienscomplexdipteraculicidae AT nagwaarashdan implicationoftheendogenousmidgutmicrobiotaoncellgenotoxicityandbiologicalfitnessofculexpipienscomplexdipteraculicidae AT refaatmgabre implicationoftheendogenousmidgutmicrobiotaoncellgenotoxicityandbiologicalfitnessofculexpipienscomplexdipteraculicidae AT emtithalmabdelsamie implicationoftheendogenousmidgutmicrobiotaoncellgenotoxicityandbiologicalfitnessofculexpipienscomplexdipteraculicidae |