Orientin Reduces the Effects of Repeated Procedural Neonatal Pain in Adulthood: Network Pharmacology Analysis, Molecular Docking Analysis, and Experimental Validation
Background. Premature infants often undergo painful procedures and consequently experience repeated procedural neonatal pain. This can elicit hyperalgesia and cognitive impairment in adulthood. Treatments for neonatal pain are limited. Orientin is a flavonoid C-glycoside that has repeatedly been sho...
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Main Authors: | Dong-Dong Guo, Hai-Yan Huang, Hai-E. Liu, Kun Liu, Xing-Jing Luo |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
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Series: | Pain Research and Management |
Online Access: | http://dx.doi.org/10.1155/2023/8893932 |
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