Overcoming immunotherapy resistance in glioblastoma: challenges and emerging strategies

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, characterized by rapid proliferation, extensive infiltration, and significant intratumoral heterogeneity. Despite advancements in conventional treatments, including surgery, radiotherapy, and chemotherapy, the progno...

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Bibliographic Details
Main Authors: Maowu Fu, Bing Xue, Xiuming Miao, Zong Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1584688/full
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