Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview

Accurate and noninvasive stem cell tracking is one of the most important needs in regenerative medicine to determine both stem cell destinations and final differentiation fates, thus allowing a more detailed picture of the mechanisms involved in these therapies. Given the great importance and advan...

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Main Authors: Lisa Accomasso, Clara Gallina, Valentina Turinetto, Claudia Giachino
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/7920358
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author Lisa Accomasso
Clara Gallina
Valentina Turinetto
Claudia Giachino
author_facet Lisa Accomasso
Clara Gallina
Valentina Turinetto
Claudia Giachino
author_sort Lisa Accomasso
collection DOAJ
description Accurate and noninvasive stem cell tracking is one of the most important needs in regenerative medicine to determine both stem cell destinations and final differentiation fates, thus allowing a more detailed picture of the mechanisms involved in these therapies. Given the great importance and advances in the field of nanotechnology for stem cell imaging, currently, several nanoparticles have become standardized products and have been undergoing fast commercialization. This review has been intended to summarize the current use of different engineered nanoparticles in stem cell tracking for regenerative medicine purposes, in particular by detailing their main features and exploring their biosafety aspects, the first step for clinical application. Moreover, this review has summarized the advantages and applications of stem cell tracking with nanoparticles in experimental and preclinical studies and investigated present limitations for their employment in the clinical setting.
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series Stem Cells International
spelling doaj-art-f0c745bdb2c048edb4b054537efe16412025-02-03T06:00:22ZengWileyStem Cells International1687-966X1687-96782016-01-01201610.1155/2016/79203587920358Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An OverviewLisa Accomasso0Clara Gallina1Valentina Turinetto2Claudia Giachino3Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyDepartment of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyDepartment of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyDepartment of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyAccurate and noninvasive stem cell tracking is one of the most important needs in regenerative medicine to determine both stem cell destinations and final differentiation fates, thus allowing a more detailed picture of the mechanisms involved in these therapies. Given the great importance and advances in the field of nanotechnology for stem cell imaging, currently, several nanoparticles have become standardized products and have been undergoing fast commercialization. This review has been intended to summarize the current use of different engineered nanoparticles in stem cell tracking for regenerative medicine purposes, in particular by detailing their main features and exploring their biosafety aspects, the first step for clinical application. Moreover, this review has summarized the advantages and applications of stem cell tracking with nanoparticles in experimental and preclinical studies and investigated present limitations for their employment in the clinical setting.http://dx.doi.org/10.1155/2016/7920358
spellingShingle Lisa Accomasso
Clara Gallina
Valentina Turinetto
Claudia Giachino
Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview
Stem Cells International
title Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview
title_full Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview
title_fullStr Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview
title_full_unstemmed Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview
title_short Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview
title_sort stem cell tracking with nanoparticles for regenerative medicine purposes an overview
url http://dx.doi.org/10.1155/2016/7920358
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AT valentinaturinetto stemcelltrackingwithnanoparticlesforregenerativemedicinepurposesanoverview
AT claudiagiachino stemcelltrackingwithnanoparticlesforregenerativemedicinepurposesanoverview