Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report
Introduction The most common cause of chiasmopathy is compression of the optic chiasm by parasellar tumours. The tumours may produce any pattern of visual field defect depending on the tumour location and the patient’s chiasmal anatomy. Rare, non-compressive causes of chiasmopathy include, among oth...
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Termedia Publishing House
2024-10-01
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| Online Access: | https://www.ophthalmologypoland.com.pl/Optic-Chiasmitis-as-an-Isolated-Manifestation-of-Myelin-Oligodendrocyte-Glycoprotein,193827,0,2.html |
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| author | Nina Barankiewicz-Tyc Karolina Kania Wojciech Kozubski |
| author_facet | Nina Barankiewicz-Tyc Karolina Kania Wojciech Kozubski |
| author_sort | Nina Barankiewicz-Tyc |
| collection | DOAJ |
| description | Introduction
The most common cause of chiasmopathy is compression of the optic chiasm by parasellar tumours. The tumours may produce any pattern of visual field defect depending on the tumour location and the patient’s chiasmal anatomy. Rare, non-compressive causes of chiasmopathy include, among others, infectious, post-infectious, inflammatory, autoimmune, demyelinating, toxic and ischaemic processes. Chiasmopathy can also occur due to trauma and radiation treatment.
Case report
We report a case of a 43-year-old patient who was admitted to our department because of a two-month history of headaches and constant, symmetrical blurriness over the temporal sides of vision. After a wide-ranging diagnostic process, the patient was diagnosed with an isolated optic chiasmitis in the course of myelin oligodendrocyte glycoprotein-associated disease, which is a rare, monophasic or relapsing, antibody-mediated inflammatory demyelinating disorder of the central nervous system.
Conclusions
It is crucial to remember that parasellar tumours are not the only cause of bitemporal hemianopsia. Patients with bitemporal hemianopsia, if there is no compressive lesion of the optic chiasm, should be investigated for optic chiasmitis. Optic chiasmitis is not a diagnosis in itself, but a sign of an underlying pathology, and during its evaluation should be treated as a variation of atypical optic neuritis. We hope that this ophthalmic manifestation of a rare neurological disease will make other clinicians aware of the utter importance of careful evaluation of visual disturbances. |
| format | Article |
| id | doaj-art-f0b5645240db4fa69ace05aa1beac19e |
| institution | Kabale University |
| issn | 1505-2753 1689-362X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Okulistyka |
| spelling | doaj-art-f0b5645240db4fa69ace05aa1beac19e2025-01-24T12:41:29ZengTermedia Publishing HouseOkulistyka1505-27531689-362X2024-10-0127381010.5114/oku/193827193827Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case ReportNina Barankiewicz-Tyc0Karolina Kania1Wojciech Kozubski2Department of Neurology, Poznan University of Medical Sciences, Poznań, Poland Head: prof. dr hab. n. med. Wojciech KozubskiDepartment of Neurology, Poznan University of Medical Sciences, Poznań, Poland Head: prof. dr hab. n. med. Wojciech KozubskiDepartment of Neurology, Poznan University of Medical Sciences, Poznań, Poland Head: prof. dr hab. n. med. Wojciech KozubskiIntroduction The most common cause of chiasmopathy is compression of the optic chiasm by parasellar tumours. The tumours may produce any pattern of visual field defect depending on the tumour location and the patient’s chiasmal anatomy. Rare, non-compressive causes of chiasmopathy include, among others, infectious, post-infectious, inflammatory, autoimmune, demyelinating, toxic and ischaemic processes. Chiasmopathy can also occur due to trauma and radiation treatment. Case report We report a case of a 43-year-old patient who was admitted to our department because of a two-month history of headaches and constant, symmetrical blurriness over the temporal sides of vision. After a wide-ranging diagnostic process, the patient was diagnosed with an isolated optic chiasmitis in the course of myelin oligodendrocyte glycoprotein-associated disease, which is a rare, monophasic or relapsing, antibody-mediated inflammatory demyelinating disorder of the central nervous system. Conclusions It is crucial to remember that parasellar tumours are not the only cause of bitemporal hemianopsia. Patients with bitemporal hemianopsia, if there is no compressive lesion of the optic chiasm, should be investigated for optic chiasmitis. Optic chiasmitis is not a diagnosis in itself, but a sign of an underlying pathology, and during its evaluation should be treated as a variation of atypical optic neuritis. We hope that this ophthalmic manifestation of a rare neurological disease will make other clinicians aware of the utter importance of careful evaluation of visual disturbances.https://www.ophthalmologypoland.com.pl/Optic-Chiasmitis-as-an-Isolated-Manifestation-of-Myelin-Oligodendrocyte-Glycoprotein,193827,0,2.htmlbitemporal hemianopsiaoptic chiasmitisoptic chiasmchiasmopathymyelin oligodendrocyte glycoprotein-associated disease (mogad)parasellar tumours |
| spellingShingle | Nina Barankiewicz-Tyc Karolina Kania Wojciech Kozubski Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report Okulistyka bitemporal hemianopsia optic chiasmitis optic chiasm chiasmopathy myelin oligodendrocyte glycoprotein-associated disease (mogad) parasellar tumours |
| title | Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report |
| title_full | Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report |
| title_fullStr | Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report |
| title_full_unstemmed | Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report |
| title_short | Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report |
| title_sort | optic chiasmitis as an isolated manifestation of myelin oligodendrocyte glycoprotein associated disease a case report |
| topic | bitemporal hemianopsia optic chiasmitis optic chiasm chiasmopathy myelin oligodendrocyte glycoprotein-associated disease (mogad) parasellar tumours |
| url | https://www.ophthalmologypoland.com.pl/Optic-Chiasmitis-as-an-Isolated-Manifestation-of-Myelin-Oligodendrocyte-Glycoprotein,193827,0,2.html |
| work_keys_str_mv | AT ninabarankiewicztyc opticchiasmitisasanisolatedmanifestationofmyelinoligodendrocyteglycoproteinassociateddiseaseacasereport AT karolinakania opticchiasmitisasanisolatedmanifestationofmyelinoligodendrocyteglycoproteinassociateddiseaseacasereport AT wojciechkozubski opticchiasmitisasanisolatedmanifestationofmyelinoligodendrocyteglycoproteinassociateddiseaseacasereport |