The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders

The advances in regenerative medicine are very important for the development of medicine and the discovery of stem cells has shown a greater capacity to raise the level of therapeutic quality while their use becomes more accessible, especially in their mesenchymal form. In veterinary medicine, it is...

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Main Authors: Alefe Luiz Caliani Carrera, Bruno Watanabe Minto, Patrícia Malard, Hilana dos Santos Sena Brunel
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.1155/2023/8819506
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author Alefe Luiz Caliani Carrera
Bruno Watanabe Minto
Patrícia Malard
Hilana dos Santos Sena Brunel
author_facet Alefe Luiz Caliani Carrera
Bruno Watanabe Minto
Patrícia Malard
Hilana dos Santos Sena Brunel
author_sort Alefe Luiz Caliani Carrera
collection DOAJ
description The advances in regenerative medicine are very important for the development of medicine and the discovery of stem cells has shown a greater capacity to raise the level of therapeutic quality while their use becomes more accessible, especially in their mesenchymal form. In veterinary medicine, it is not different. The use of those cells, as well as recent advances related to the use of their extracellular vesicles, demonstrates a great opportunity to enhance therapeutic methods and ensure more life quality for patients, which can be in clinical or surgical treatments. Knowing the advances in these modalities and the growing clinical and surgery research and demands for innovations in orthopedic and neurology medicines, this paper aimed to review the literature about the methodologies of use and applications such as the pathways of action and the advances that were postulated for microvesicles and exosomes derived from mesenchymal stem cells in veterinary medicine, especially for musculoskeletal disorders and related injuries.
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institution Kabale University
issn 2042-0048
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publishDate 2023-01-01
publisher Wiley
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series Veterinary Medicine International
spelling doaj-art-f0aa096b38d54dc2a6815c3c92125ba42025-02-03T06:43:07ZengWileyVeterinary Medicine International2042-00482023-01-01202310.1155/2023/8819506The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related DisordersAlefe Luiz Caliani Carrera0Bruno Watanabe Minto1Patrícia Malard2Hilana dos Santos Sena Brunel3Department of Clinical and Veterinary SurgeryDepartment of Clinical and Veterinary SurgeryCatholic University of BrasiliaCatholic University of BrasiliaThe advances in regenerative medicine are very important for the development of medicine and the discovery of stem cells has shown a greater capacity to raise the level of therapeutic quality while their use becomes more accessible, especially in their mesenchymal form. In veterinary medicine, it is not different. The use of those cells, as well as recent advances related to the use of their extracellular vesicles, demonstrates a great opportunity to enhance therapeutic methods and ensure more life quality for patients, which can be in clinical or surgical treatments. Knowing the advances in these modalities and the growing clinical and surgery research and demands for innovations in orthopedic and neurology medicines, this paper aimed to review the literature about the methodologies of use and applications such as the pathways of action and the advances that were postulated for microvesicles and exosomes derived from mesenchymal stem cells in veterinary medicine, especially for musculoskeletal disorders and related injuries.http://dx.doi.org/10.1155/2023/8819506
spellingShingle Alefe Luiz Caliani Carrera
Bruno Watanabe Minto
Patrícia Malard
Hilana dos Santos Sena Brunel
The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders
Veterinary Medicine International
title The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders
title_full The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders
title_fullStr The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders
title_full_unstemmed The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders
title_short The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders
title_sort role of mesenchymal stem cell secretome extracellular microvesicles and exosomes in animals musculoskeletal and neurologic related disorders
url http://dx.doi.org/10.1155/2023/8819506
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