A novel kinetic model estimating the urea concentration in plasma during non-invasive sweat-based monitoring in hemodialysis

A novel kinetic model estimating the urea concentration in plasma during non-invasive sweat-based monitoring in hemodialysis

IntroductionThe adequacy of hemodialysis (HD) in patients with end-stage renal disease is evaluated frequently by monitoring changes in blood urea concentrations multiple times between treatments. As monitoring of urea concentrations typically requires blood sampling, the development of sweat-sensin...

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Bibliographic Details
Main Authors: Xiaoyu Yin, Sophie Adelaars, Elisabetta Peri, Eduard Pelssers, Jaap Den Toonder, Arthur Bouwman, Daan Van de Kerkhof, Massimo Mischi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Physiology
Subjects:
kidney failure
end-stage renal disease
patient monitoring
pharmacokinetic modeling
inverse modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1547117/full
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