Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications
Introduction Xerostomia is a subjective sensation of dry mouth due to lack of saliva. The objective of this study was to investigate the prevalence and factors associated with the presence of hypo-salivation and xerostomia complaint in patients with human immunodeficiency virus (HIV) and acquired im...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2024-10-01
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| Series: | HIV & AIDS Review. International Journal of HIV-Related Problems |
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| author | Jhonatan Yukio Naka Adryano Arana Kamei Vanessa C. Klamas Mateus A. Ventura Marcelo Morato Rafael Z. Mobile Antonio A. S. D. Lima |
| author_facet | Jhonatan Yukio Naka Adryano Arana Kamei Vanessa C. Klamas Mateus A. Ventura Marcelo Morato Rafael Z. Mobile Antonio A. S. D. Lima |
| author_sort | Jhonatan Yukio Naka |
| collection | DOAJ |
| description | Introduction
Xerostomia is a subjective sensation of dry mouth due to lack of saliva. The objective of this study was to investigate the prevalence and factors associated with the presence of hypo-salivation and xerostomia complaint in patients with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)-related complications.
Material and methods
One hundred and two adult subjects were divided into two groups (51 HIV-infected patients and 51 controls). Initially, subjects underwent oral examination and anamnesis. Afterwards, stimulated salivary flow and a questionnaire to evaluate the prevalence and intensity of xerostomia symptoms were utilized.
Results
The mean salivary flow was significantly lower in HIV-positive individuals compared with controls. Twenty-five (49%) patients with HIV infection experienced low salivary flow. The complaint of xerostomia was reported by 30 (59%) patients and 9 (18%) controls. The sensation of discomfort in the mouth, and difficulty in talking and eating had greater records of moderate to severe intensity in the case group. Of the total sample, 76% of individuals used antiretroviral therapy and other drugs capable of inducing hypo-salivation and, consequently, xerostomia.
Conclusions
Based on the results, it can be concluded that the prevalence of xerostomia among hospitalized patients due to AIDS complications is high. This fact may be associated with low salivary flow and the use of various drugs, including antiretroviral drugs. |
| format | Article |
| id | doaj-art-f074533baa5e41d79ee4a6e2592b6b7c |
| institution | Kabale University |
| issn | 1730-1270 1732-2707 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | HIV & AIDS Review. International Journal of HIV-Related Problems |
| spelling | doaj-art-f074533baa5e41d79ee4a6e2592b6b7c2025-01-27T11:06:39ZengTermedia Publishing HouseHIV & AIDS Review. International Journal of HIV-Related Problems1730-12701732-27072024-10-0123429029610.5114/hivar/151785151785Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complicationsJhonatan Yukio Naka0Adryano Arana Kamei1Vanessa C. Klamas2Mateus A. Ventura3Marcelo Morato4Rafael Z. Mobile5https://orcid.org/0000-0002-8603-2614Antonio A. S. D. Lima6https://orcid.org/0000-0002-9522-6832Universidade Federal do Paraná – UFPR, BrazilUniversidade Federal do Paraná – UFPR, BrazilUniversidade Federal do Paraná – UFPR, BrazilUniversidade Federal do Paraná – UFPR, BrazilUniversidade Federal do Paraná – UFPR, BrazilUniversidade Federal do Paraná – UFPR, BrazilUniversidade Federal do Paraná – UFPR, BrazilIntroduction Xerostomia is a subjective sensation of dry mouth due to lack of saliva. The objective of this study was to investigate the prevalence and factors associated with the presence of hypo-salivation and xerostomia complaint in patients with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)-related complications. Material and methods One hundred and two adult subjects were divided into two groups (51 HIV-infected patients and 51 controls). Initially, subjects underwent oral examination and anamnesis. Afterwards, stimulated salivary flow and a questionnaire to evaluate the prevalence and intensity of xerostomia symptoms were utilized. Results The mean salivary flow was significantly lower in HIV-positive individuals compared with controls. Twenty-five (49%) patients with HIV infection experienced low salivary flow. The complaint of xerostomia was reported by 30 (59%) patients and 9 (18%) controls. The sensation of discomfort in the mouth, and difficulty in talking and eating had greater records of moderate to severe intensity in the case group. Of the total sample, 76% of individuals used antiretroviral therapy and other drugs capable of inducing hypo-salivation and, consequently, xerostomia. Conclusions Based on the results, it can be concluded that the prevalence of xerostomia among hospitalized patients due to AIDS complications is high. This fact may be associated with low salivary flow and the use of various drugs, including antiretroviral drugs.https://hivaids.termedia.pl/Prevalence-and-factors-associated-with-xerostomia-in-patients-hospitalized-due-AIDS,151785,0,2.htmlxerostomiaacquired immunodeficiency syndromesalivasalivationdrug-related side effectsadverse reactions |
| spellingShingle | Jhonatan Yukio Naka Adryano Arana Kamei Vanessa C. Klamas Mateus A. Ventura Marcelo Morato Rafael Z. Mobile Antonio A. S. D. Lima Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications HIV & AIDS Review. International Journal of HIV-Related Problems xerostomia acquired immunodeficiency syndrome saliva salivation drug-related side effects adverse reactions |
| title | Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications |
| title_full | Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications |
| title_fullStr | Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications |
| title_full_unstemmed | Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications |
| title_short | Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications |
| title_sort | prevalence and factors associated with xerostomia in patients hospitalized due aids related complications |
| topic | xerostomia acquired immunodeficiency syndrome saliva salivation drug-related side effects adverse reactions |
| url | https://hivaids.termedia.pl/Prevalence-and-factors-associated-with-xerostomia-in-patients-hospitalized-due-AIDS,151785,0,2.html |
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