Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review

BackgroundGender is known to have a strong influence on human health and disease. Despite its relevance to treatment and outcome, gender is insufficiently considered in current health research. One hindering factor is the poor representation of gender information in clinical...

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Main Authors: Lea Schindler, Hilke Beelich, Selina Röll, Elpiniki Katsari, Sylvia Stracke, Dagmar Waltemath
Format: Article
Language:English
Published: JMIR Publications 2025-01-01
Series:JMIR Research Protocols
Online Access:https://www.researchprotocols.org/2025/1/e57669
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author Lea Schindler
Hilke Beelich
Selina Röll
Elpiniki Katsari
Sylvia Stracke
Dagmar Waltemath
author_facet Lea Schindler
Hilke Beelich
Selina Röll
Elpiniki Katsari
Sylvia Stracke
Dagmar Waltemath
author_sort Lea Schindler
collection DOAJ
description BackgroundGender is known to have a strong influence on human health and disease. Despite its relevance to treatment and outcome, gender is insufficiently considered in current health research. One hindering factor is the poor representation of gender information in clinical and health (meta) data. ObjectiveWe aim to conduct a scoping review of the literature describing gender scores. The review will provide insights into the current application of gender scores in clinical and health settings. The protocol describes how relevant literature will be identified and how gender scores will be evaluated concerning applicability and usability in scientific investigations. MethodsOur scoping review follows the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. A title and abstract screening was conducted on PubMed, followed by a full-text screening. The inclusion and exclusion criteria were discussed by a team of 5 domain experts, and a data-charting form was developed. The charted data will be categorized, summarized, and analyzed based on the research questions during the scoping review. ResultsWe will report our research results according to the PRISMA-ScR guidelines. The literature retrieval was carried out on June 13, 2024, and resulted in 1202 matches. As of July 2024, the scoping review is in the data extraction phase and we expect to complete and publish the results in the first quarter of 2025. ConclusionsThe scoping review lays the foundation for a retrospective gender assessment by identifying scores that can be applied to existing large-scale datasets. Moreover, it will help to formulate recommendations for standardized gender scores in future investigations. International Registered Report Identifier (IRRID)DERR1-10.2196/57669
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spelling doaj-art-f065d4fc1e6f4645863ea10ade81862e2025-01-20T15:30:51ZengJMIR PublicationsJMIR Research Protocols1929-07482025-01-0114e5766910.2196/57669Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping ReviewLea Schindlerhttps://orcid.org/0009-0002-3408-2385Hilke Beelichhttps://orcid.org/0009-0007-7296-8642Selina Röllhttps://orcid.org/0009-0006-6970-9335Elpiniki Katsarihttps://orcid.org/0000-0003-1956-8192Sylvia Strackehttps://orcid.org/0000-0001-6200-4339Dagmar Waltemathhttps://orcid.org/0000-0002-5886-5563 BackgroundGender is known to have a strong influence on human health and disease. Despite its relevance to treatment and outcome, gender is insufficiently considered in current health research. One hindering factor is the poor representation of gender information in clinical and health (meta) data. ObjectiveWe aim to conduct a scoping review of the literature describing gender scores. The review will provide insights into the current application of gender scores in clinical and health settings. The protocol describes how relevant literature will be identified and how gender scores will be evaluated concerning applicability and usability in scientific investigations. MethodsOur scoping review follows the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. A title and abstract screening was conducted on PubMed, followed by a full-text screening. The inclusion and exclusion criteria were discussed by a team of 5 domain experts, and a data-charting form was developed. The charted data will be categorized, summarized, and analyzed based on the research questions during the scoping review. ResultsWe will report our research results according to the PRISMA-ScR guidelines. The literature retrieval was carried out on June 13, 2024, and resulted in 1202 matches. As of July 2024, the scoping review is in the data extraction phase and we expect to complete and publish the results in the first quarter of 2025. ConclusionsThe scoping review lays the foundation for a retrospective gender assessment by identifying scores that can be applied to existing large-scale datasets. Moreover, it will help to formulate recommendations for standardized gender scores in future investigations. International Registered Report Identifier (IRRID)DERR1-10.2196/57669https://www.researchprotocols.org/2025/1/e57669
spellingShingle Lea Schindler
Hilke Beelich
Selina Röll
Elpiniki Katsari
Sylvia Stracke
Dagmar Waltemath
Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review
JMIR Research Protocols
title Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review
title_full Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review
title_fullStr Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review
title_full_unstemmed Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review
title_short Applicability of Retrospective and Prospective Gender Scores for Clinical and Health Data: Protocol for a Scoping Review
title_sort applicability of retrospective and prospective gender scores for clinical and health data protocol for a scoping review
url https://www.researchprotocols.org/2025/1/e57669
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