Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature

A case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after...

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Main Authors: Annahita Amireskandari, Andrew Bean, Thomas Mauger
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2021/5526097
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author Annahita Amireskandari
Andrew Bean
Thomas Mauger
author_facet Annahita Amireskandari
Andrew Bean
Thomas Mauger
author_sort Annahita Amireskandari
collection DOAJ
description A case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after oral and topical fluoroquinolone exposure. Additionally, we review the literature on safety, efficacy, and appropriate dosing of intracameral antibiotics with a focus on moxifloxacin.
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-f05043db5cb2413aac6afa11c02b1c6e2025-02-03T01:09:56ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/55260975526097Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the LiteratureAnnahita Amireskandari0Andrew Bean1Thomas Mauger2Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, USADepartment of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, USADepartment of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, USAA case of severe anterior segment toxicity secondary to high-volume, undiluted intracameral moxifloxacin for endophthalmitis prophylaxis is reported. We examine the other reported cases of toxicity after intracameral moxifloxacin, as well as iris depigmentation and transillumination syndromes after oral and topical fluoroquinolone exposure. Additionally, we review the literature on safety, efficacy, and appropriate dosing of intracameral antibiotics with a focus on moxifloxacin.http://dx.doi.org/10.1155/2021/5526097
spellingShingle Annahita Amireskandari
Andrew Bean
Thomas Mauger
Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
Case Reports in Ophthalmological Medicine
title Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_full Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_fullStr Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_full_unstemmed Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_short Toxic Anterior Segment Syndrome with Intracameral Moxifloxacin: Case Report and Review of the Literature
title_sort toxic anterior segment syndrome with intracameral moxifloxacin case report and review of the literature
url http://dx.doi.org/10.1155/2021/5526097
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AT thomasmauger toxicanteriorsegmentsyndromewithintracameralmoxifloxacincasereportandreviewoftheliterature