Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective Formulations
Rhabdophane, CePO<sub>4</sub>∙H<sub>2</sub>O, nanoparticles were prepared by mechanochemical synthesis with different durations and thoroughly characterized by various characterization techniques. X-ray diffraction analysis showed that the optimal synthesis duration was 15 mi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/30/2/405 |
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| author | Stanislav Kurajica Filip Brleković Sabina Keser Goran Dražić Katarina Mužina Vanesa Mihajlović |
| author_facet | Stanislav Kurajica Filip Brleković Sabina Keser Goran Dražić Katarina Mužina Vanesa Mihajlović |
| author_sort | Stanislav Kurajica |
| collection | DOAJ |
| description | Rhabdophane, CePO<sub>4</sub>∙H<sub>2</sub>O, nanoparticles were prepared by mechanochemical synthesis with different durations and thoroughly characterized by various characterization techniques. X-ray diffraction analysis showed that the optimal synthesis duration was 15 min, since, in this case, pure rhabdophane is obtained, without traces of contamination by the vessel material. The size of the obtained nanoparticles, as determined from high-resolution transmission electron microscopy images, was around 5 nm. According to UV-Vis diffuse reflectance spectroscopy results, rhabdophane nanoparticles show transparency to visible light and high absorption in the UV region, with a direct bandgap of 3.1 eV. The photocatalytic activity in the Castor oil degradation process and the cytotoxicity for human skin cells were determined and compared to commercial TiO<sub>2</sub> nanoparticles, with rhabdophane nanoparticles exhibiting superior properties. Small particle size, purity, absorption in the UV range, transparency to visible light, low photocatalytic activity, and low cytotoxicity indicated the possibility of prepared rhabdophane application as an inorganic UV filter in photoprotective formulations. |
| format | Article |
| id | doaj-art-f032fe0713d247d6b5507f7be2151f6a |
| institution | Kabale University |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
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| series | Molecules |
| spelling | doaj-art-f032fe0713d247d6b5507f7be2151f6a2025-01-24T13:43:55ZengMDPI AGMolecules1420-30492025-01-0130240510.3390/molecules30020405Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective FormulationsStanislav Kurajica0Filip Brleković1Sabina Keser2Goran Dražić3Katarina Mužina4Vanesa Mihajlović5Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR 10000 Zagreb, CroatiaFaculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR 10000 Zagreb, CroatiaFaculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR 10000 Zagreb, CroatiaNational Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, SloveniaFaculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR 10000 Zagreb, CroatiaFaculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR 10000 Zagreb, CroatiaRhabdophane, CePO<sub>4</sub>∙H<sub>2</sub>O, nanoparticles were prepared by mechanochemical synthesis with different durations and thoroughly characterized by various characterization techniques. X-ray diffraction analysis showed that the optimal synthesis duration was 15 min, since, in this case, pure rhabdophane is obtained, without traces of contamination by the vessel material. The size of the obtained nanoparticles, as determined from high-resolution transmission electron microscopy images, was around 5 nm. According to UV-Vis diffuse reflectance spectroscopy results, rhabdophane nanoparticles show transparency to visible light and high absorption in the UV region, with a direct bandgap of 3.1 eV. The photocatalytic activity in the Castor oil degradation process and the cytotoxicity for human skin cells were determined and compared to commercial TiO<sub>2</sub> nanoparticles, with rhabdophane nanoparticles exhibiting superior properties. Small particle size, purity, absorption in the UV range, transparency to visible light, low photocatalytic activity, and low cytotoxicity indicated the possibility of prepared rhabdophane application as an inorganic UV filter in photoprotective formulations.https://www.mdpi.com/1420-3049/30/2/405cerium phosphatemechanochemical synthesisUV filtercytotoxicityphotoprotection |
| spellingShingle | Stanislav Kurajica Filip Brleković Sabina Keser Goran Dražić Katarina Mužina Vanesa Mihajlović Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective Formulations Molecules cerium phosphate mechanochemical synthesis UV filter cytotoxicity photoprotection |
| title | Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective Formulations |
| title_full | Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective Formulations |
| title_fullStr | Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective Formulations |
| title_full_unstemmed | Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective Formulations |
| title_short | Evaluation of Mechanochemically Prepared CePO<sub>4</sub>∙H<sub>2</sub>O Nanoparticles as UV Filter for Photoprotective Formulations |
| title_sort | evaluation of mechanochemically prepared cepo sub 4 sub ∙h sub 2 sub o nanoparticles as uv filter for photoprotective formulations |
| topic | cerium phosphate mechanochemical synthesis UV filter cytotoxicity photoprotection |
| url | https://www.mdpi.com/1420-3049/30/2/405 |
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