The research on cycloastragenol in the treatment of brain metastases from lung cancer: mechanistic exploration of radiotherapy sensitization and amelioration of brain injury

The research on cycloastragenol in the treatment of brain metastases from lung cancer: mechanistic exploration of radiotherapy sensitization and amelioration of brain injury

ObjectiveThis study aimed to investigate the radiosensitizing and toxicity-reducing effects of Cycloastragenol (CAG) in the radiotherapy of lung cancer brain metastases.MethodsA brain metastasis model of lung cancer was established using stereotactic brain localization. After successful modeling, va...

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Bibliographic Details
Main Authors: Yanyan Tao, Jingwen Chang, Xinyi Zhu, Jingjing Han, Xinru Wang, Yun Sheng, Ziyi Sun, Fang Liu, Yu Tao, Hongyan Wu, Chen Yu, Hao Liu, Fangtian Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
Subjects:
Cycloastragenol
neutrophil Infiltration
neuroinflammation
lung cancer brain metastases
radiation-induced brain injury
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1616894/full
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