Effects of Common Anti-Inflammatories on Adenovirus Entry and Their Physicochemical Properties: An In-Depth Study Using Cellular and Animal Models

Effects of Common Anti-Inflammatories on Adenovirus Entry and Their Physicochemical Properties: An In-Depth Study Using Cellular and Animal Models

The severity of adenovirus infection or the success of adenovirus-vectorized gene therapy largely depends on the efficiency of viral entry into cells. Various drugs can alter viral entry. This study evaluated the effects of dexamethasone, paracetamol, diclofenac, ibuprofen, and ketorolac on adenovir...

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Main Authors: Hector R. Galvan-Salazar, Marina Delgado-Machuca, Gustavo A. Hernandez-Fuentes, Nomely S. Aurelien-Cabezas, Alejandrina Rodriguez-Hernandez, Idalia Garza-Veloz, Martha A. Mendoza-Hernandez, Margarita L. Martinez-Fierro, Sergio A. Zaizar-Fregoso, Iram P. Rodriguez-Sanchez, Fabian Rojas-Larios, Mario Del-Toro-Equihua, Gabriel Ceja-Espiritu, Ivan Delgado-Enciso
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Microbiology Research
Subjects:
anti-inflammatory drugs
adenovirus
adenoviral vector
infection
gene therapy
vaccines
Online Access:https://www.mdpi.com/2036-7481/15/3/105
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