Acute Eosinophilic Ascites in a Middle-Aged Man
Eosinophilic gastroenteritis is a rare condition characterized by recurrent eosinophilic infiltration of portions of the GI tract and presenting with nonspecific GI symptoms in association with peripheral eosinophilia. Its etiology and pathogenesis remain unclear and its symptoms overlap with many G...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | Case Reports in Gastrointestinal Medicine |
Online Access: | http://dx.doi.org/10.1155/2012/896523 |
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author | Fadi Bleibel Keith Fragoza Garrey T. Faller |
author_facet | Fadi Bleibel Keith Fragoza Garrey T. Faller |
author_sort | Fadi Bleibel |
collection | DOAJ |
description | Eosinophilic gastroenteritis is a rare condition characterized by recurrent eosinophilic infiltration of portions of the GI tract and presenting with nonspecific GI symptoms in association with peripheral eosinophilia. Its etiology and pathogenesis remain unclear and its symptoms overlap with many GI and systemic diseases. Thus, both gastroenterologists and general internists need to be aware of this rare condition. We present a case of a 55-year-old male with diffuse abdominal pain and distention for two weeks. His physical examination was significant for moderate ascites. Initial work-up demonstrated severe peripheral blood eosinophilia, normal liver function tests, thickening of the stomach and small bowel wall, and elevated serum IgE. Upper endoscopy and extensive testing for malignancy and parasitic infections failed to establish a diagnosis. Ascitic fluid analysis showed significant eosinophilia. Further, a full-thickness jejunal showed marked eosinophilic infiltration of the serosa and muscularis propria. Subsequent treatment with oral prednisone resulted in normalization of laboratory and radiologic abnormalities in a few week period. |
format | Article |
id | doaj-art-efdb351220f345cfb98cf2bd7a659633 |
institution | Kabale University |
issn | 2090-6528 2090-6536 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Gastrointestinal Medicine |
spelling | doaj-art-efdb351220f345cfb98cf2bd7a6596332025-02-03T06:07:21ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362012-01-01201210.1155/2012/896523896523Acute Eosinophilic Ascites in a Middle-Aged ManFadi Bleibel0Keith Fragoza1Garrey T. Faller2Department of Internal Medicine, Steward Carney Hospital, Tufts University, Boston, MA 02124, USADepartment of Internal Medicine, Steward Carney Hospital, Tufts University, Boston, MA 02124, USADepartment of Pathology, Steward Carney Hospital, Tufts University, Boston, MA 02124, USAEosinophilic gastroenteritis is a rare condition characterized by recurrent eosinophilic infiltration of portions of the GI tract and presenting with nonspecific GI symptoms in association with peripheral eosinophilia. Its etiology and pathogenesis remain unclear and its symptoms overlap with many GI and systemic diseases. Thus, both gastroenterologists and general internists need to be aware of this rare condition. We present a case of a 55-year-old male with diffuse abdominal pain and distention for two weeks. His physical examination was significant for moderate ascites. Initial work-up demonstrated severe peripheral blood eosinophilia, normal liver function tests, thickening of the stomach and small bowel wall, and elevated serum IgE. Upper endoscopy and extensive testing for malignancy and parasitic infections failed to establish a diagnosis. Ascitic fluid analysis showed significant eosinophilia. Further, a full-thickness jejunal showed marked eosinophilic infiltration of the serosa and muscularis propria. Subsequent treatment with oral prednisone resulted in normalization of laboratory and radiologic abnormalities in a few week period.http://dx.doi.org/10.1155/2012/896523 |
spellingShingle | Fadi Bleibel Keith Fragoza Garrey T. Faller Acute Eosinophilic Ascites in a Middle-Aged Man Case Reports in Gastrointestinal Medicine |
title | Acute Eosinophilic Ascites in a Middle-Aged Man |
title_full | Acute Eosinophilic Ascites in a Middle-Aged Man |
title_fullStr | Acute Eosinophilic Ascites in a Middle-Aged Man |
title_full_unstemmed | Acute Eosinophilic Ascites in a Middle-Aged Man |
title_short | Acute Eosinophilic Ascites in a Middle-Aged Man |
title_sort | acute eosinophilic ascites in a middle aged man |
url | http://dx.doi.org/10.1155/2012/896523 |
work_keys_str_mv | AT fadibleibel acuteeosinophilicascitesinamiddleagedman AT keithfragoza acuteeosinophilicascitesinamiddleagedman AT garreytfaller acuteeosinophilicascitesinamiddleagedman |