Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus
Objective. To report a case of diabetic muscle infarction (DMI), a rare complication of long-standing poorly controlled diabetes mellitus. Methods. We describe a case of a 45-year-old male with an approximately 8-year history of poorly controlled type 2 diabetes mellitus with multiple microvascular...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/407921 |
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| author | Shridhar N. Iyer Almond J. Drake R. Lee West Robert J. Tanenberg |
| author_facet | Shridhar N. Iyer Almond J. Drake R. Lee West Robert J. Tanenberg |
| author_sort | Shridhar N. Iyer |
| collection | DOAJ |
| description | Objective. To report a case of diabetic muscle infarction (DMI), a rare complication of long-standing poorly controlled diabetes mellitus. Methods. We describe a case of a 45-year-old male with an approximately 8-year history of poorly controlled type 2 diabetes mellitus with multiple microvascular complications who presented with the sudden onset of left thigh pain and swelling. He had a swollen left thigh and a CK of 1670 U/L. He was initially treated with intravenous antibiotics for a presumptive diagnosis of pyomyositis or necrotizing fasciitis with no improvement. A diagnosis of diabetic muscle infarction was considered. Results. An MRI of the thigh demonstrated diffuse edema in the anterior compartment. A muscle biopsy demonstrated coagulation necrosis in skeletal muscle and inflammation and infarction in the walls of small blood vessels. These studies confirmed the final diagnosis of DMI. He was treated with supportive care and gradually improved. Conclusion. DMI is a rare complication of diabetes that is often mistaken for infections such as pyomyositis and necrotizing fasciitis or thrombophlebitis. Treatment is supportive. Although the short-term prognosis is good in these patients, the long-term prognosis is poor. |
| format | Article |
| id | doaj-art-efbb8acc85484aadbfa6d0dbd9515905 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-efbb8acc85484aadbfa6d0dbd95159052025-02-03T01:11:22ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/407921407921Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes MellitusShridhar N. Iyer0Almond J. Drake1R. Lee West2Robert J. Tanenberg3Division of General Internal Medicine, Department of Internal Medicine, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USADivision of Endocrinology, Department of Internal Medicine, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USADepartment of Pathology, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USADivision of Endocrinology, Department of Internal Medicine, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USAObjective. To report a case of diabetic muscle infarction (DMI), a rare complication of long-standing poorly controlled diabetes mellitus. Methods. We describe a case of a 45-year-old male with an approximately 8-year history of poorly controlled type 2 diabetes mellitus with multiple microvascular complications who presented with the sudden onset of left thigh pain and swelling. He had a swollen left thigh and a CK of 1670 U/L. He was initially treated with intravenous antibiotics for a presumptive diagnosis of pyomyositis or necrotizing fasciitis with no improvement. A diagnosis of diabetic muscle infarction was considered. Results. An MRI of the thigh demonstrated diffuse edema in the anterior compartment. A muscle biopsy demonstrated coagulation necrosis in skeletal muscle and inflammation and infarction in the walls of small blood vessels. These studies confirmed the final diagnosis of DMI. He was treated with supportive care and gradually improved. Conclusion. DMI is a rare complication of diabetes that is often mistaken for infections such as pyomyositis and necrotizing fasciitis or thrombophlebitis. Treatment is supportive. Although the short-term prognosis is good in these patients, the long-term prognosis is poor.http://dx.doi.org/10.1155/2011/407921 |
| spellingShingle | Shridhar N. Iyer Almond J. Drake R. Lee West Robert J. Tanenberg Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus Case Reports in Medicine |
| title | Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus |
| title_full | Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus |
| title_fullStr | Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus |
| title_full_unstemmed | Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus |
| title_short | Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus |
| title_sort | diabetic muscle infarction a rare complication of long standing and poorly controlled diabetes mellitus |
| url | http://dx.doi.org/10.1155/2011/407921 |
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