Vascular embolization combined with amputation for recurrent hemophilic pseudotumor
Abstract Hemophilic pseudotumor is a rare, life - threatening complication of hemophilia. Surgical treatment presents substantial challenges, particularly in coagulation management, perioperative wound healing, and infection control. We present a case of recurrent pseudotumor with refractory wound h...
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| Format: | Article |
| Language: | English |
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BMC
2025-08-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-025-09031-x |
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| author | Shuaijie Lv Lei Chen Yi Tang Yichen Gong Peijian Tong Jiayi Guo Zhongyi Zhang |
| author_facet | Shuaijie Lv Lei Chen Yi Tang Yichen Gong Peijian Tong Jiayi Guo Zhongyi Zhang |
| author_sort | Shuaijie Lv |
| collection | DOAJ |
| description | Abstract Hemophilic pseudotumor is a rare, life - threatening complication of hemophilia. Surgical treatment presents substantial challenges, particularly in coagulation management, perioperative wound healing, and infection control. We present a case of recurrent pseudotumor with refractory wound healing following multiple surgical interventions, which was successfully managed through a multidisciplinary approach combining vascular embolization with amputation. The case involves a 28-year-old male patient with hemophilia-associated pseudotumor who presented with a two-year history of impaired wound healing following right above-knee amputation. Clinical examination revealed significant swelling and tenderness in the right thigh region, accompanied by persistent drainage of black viscous exudate from the surgical site. Due to pseudotumor recurrence and chronic wound complications, a multidisciplinary team comprising hematology, interventional radiology, and orthopedic specialists implemented a combined therapeutic strategy of preoperative vascular embolization followed by definitive amputation. The postoperative course demonstrated favorable outcomes, with complete wound healing and no evidence of disease recurrence during the 6-month follow-up observation period. |
| format | Article |
| id | doaj-art-ef973f1f99e340628ef2690bdc8b0e1a |
| institution | Kabale University |
| issn | 1471-2474 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj-art-ef973f1f99e340628ef2690bdc8b0e1a2025-08-20T03:45:43ZengBMCBMC Musculoskeletal Disorders1471-24742025-08-012611710.1186/s12891-025-09031-xVascular embolization combined with amputation for recurrent hemophilic pseudotumorShuaijie Lv0Lei Chen1Yi Tang2Yichen Gong3Peijian Tong4Jiayi Guo5Zhongyi Zhang6The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)Luoyang Orthopedic-Traumatological Hospital of Hehan Province (Henan Provincial Orthopedic Hospital)The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)Abstract Hemophilic pseudotumor is a rare, life - threatening complication of hemophilia. Surgical treatment presents substantial challenges, particularly in coagulation management, perioperative wound healing, and infection control. We present a case of recurrent pseudotumor with refractory wound healing following multiple surgical interventions, which was successfully managed through a multidisciplinary approach combining vascular embolization with amputation. The case involves a 28-year-old male patient with hemophilia-associated pseudotumor who presented with a two-year history of impaired wound healing following right above-knee amputation. Clinical examination revealed significant swelling and tenderness in the right thigh region, accompanied by persistent drainage of black viscous exudate from the surgical site. Due to pseudotumor recurrence and chronic wound complications, a multidisciplinary team comprising hematology, interventional radiology, and orthopedic specialists implemented a combined therapeutic strategy of preoperative vascular embolization followed by definitive amputation. The postoperative course demonstrated favorable outcomes, with complete wound healing and no evidence of disease recurrence during the 6-month follow-up observation period.https://doi.org/10.1186/s12891-025-09031-xHemophilic pseudotumorAmputationVascular embolizationMultidisciplinary approach |
| spellingShingle | Shuaijie Lv Lei Chen Yi Tang Yichen Gong Peijian Tong Jiayi Guo Zhongyi Zhang Vascular embolization combined with amputation for recurrent hemophilic pseudotumor BMC Musculoskeletal Disorders Hemophilic pseudotumor Amputation Vascular embolization Multidisciplinary approach |
| title | Vascular embolization combined with amputation for recurrent hemophilic pseudotumor |
| title_full | Vascular embolization combined with amputation for recurrent hemophilic pseudotumor |
| title_fullStr | Vascular embolization combined with amputation for recurrent hemophilic pseudotumor |
| title_full_unstemmed | Vascular embolization combined with amputation for recurrent hemophilic pseudotumor |
| title_short | Vascular embolization combined with amputation for recurrent hemophilic pseudotumor |
| title_sort | vascular embolization combined with amputation for recurrent hemophilic pseudotumor |
| topic | Hemophilic pseudotumor Amputation Vascular embolization Multidisciplinary approach |
| url | https://doi.org/10.1186/s12891-025-09031-x |
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