Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances

The development of immunocompetent skin models marks a significant advancement in in vitro methods for detecting skin sensitizers while adhering to the 3R principles, which aim to reduce, refine, and replace animal testing. This study introduces for the first time an advanced immunocompetent skin mo...

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Bibliographic Details
Main Authors: Marla Dubau, Tarada Tripetchr, Lava Mahmoud, Fabian Schumacher, Burkhard Kleuser
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314251336296
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