Pulmonary Histoplasmosis in a Referral Hospital in Mexico City
Pulmonary histoplasmosis is caused by inhaling Histoplasma capsulatum. Less than 1% develops the disease. Risk factors in immunocompetent individuals are environmental exposures in endemic areas. The objective of this study is to determine the frequency, clinical, and microbiological characteristics...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2022/2121714 |
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| author | Alejandro Hernández Solís Javier Araiza Santibáñez Jazmín Guadalupe Tejeda Olán Andrea Quintana Martínez Alejandro Hernández de la Torriente Rocio de la Torriente Mata |
| author_facet | Alejandro Hernández Solís Javier Araiza Santibáñez Jazmín Guadalupe Tejeda Olán Andrea Quintana Martínez Alejandro Hernández de la Torriente Rocio de la Torriente Mata |
| author_sort | Alejandro Hernández Solís |
| collection | DOAJ |
| description | Pulmonary histoplasmosis is caused by inhaling Histoplasma capsulatum. Less than 1% develops the disease. Risk factors in immunocompetent individuals are environmental exposures in endemic areas. The objective of this study is to determine the frequency, clinical, and microbiological characteristics in immunocompetent patients. A retrospective case series study of patients diagnosed with pulmonary histoplasmosis was performed in a respiratory care unit in Mexico City from 2000 to 2020. Each patient had bronchial lavage, and three patients underwent thoracoscopy for the lung tissue sample taken for the culture in Sabouraud Dextrose Agar. Twelve patients were identified, 8 males and 4 females; the predominant symptoms were fever (83%), dyspnea (75%), chest pain (66%), hemoptysis (41%), and weight loss (33%). The computed tomography of the chest showed the following findings: patchy consolidation 12 (100%), hilar adenopathy 6 (50%), pleural effusion 6 (50%), caverns 3 (25%), and solitary pulmonary nodule in one patient (8%). Histoplasma capsulatum was found in the culture of all twelve patients. The signs and symptoms of the disease are mediated by the immune status of the host. The clinical picture is often confused with systemic diseases. It is important to have a high degree of clinical suspicion to make a timely diagnosis. |
| format | Article |
| id | doaj-art-ef7a9421c5b543c184ebe418a08c5ca1 |
| institution | Kabale University |
| issn | 1918-1493 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-ef7a9421c5b543c184ebe418a08c5ca12025-02-03T01:33:27ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932022-01-01202210.1155/2022/2121714Pulmonary Histoplasmosis in a Referral Hospital in Mexico CityAlejandro Hernández Solís0Javier Araiza Santibáñez1Jazmín Guadalupe Tejeda Olán2Andrea Quintana Martínez3Alejandro Hernández de la Torriente4Rocio de la Torriente Mata5Servicio de Neumología y Cirugía de TóraxLaboratorio de MicologíaLaboratorio de MicologíaServicio de Neumología y Cirugía de TóraxFacultad de Estudios Superiores Cuautitlán IzcalliIMSSPulmonary histoplasmosis is caused by inhaling Histoplasma capsulatum. Less than 1% develops the disease. Risk factors in immunocompetent individuals are environmental exposures in endemic areas. The objective of this study is to determine the frequency, clinical, and microbiological characteristics in immunocompetent patients. A retrospective case series study of patients diagnosed with pulmonary histoplasmosis was performed in a respiratory care unit in Mexico City from 2000 to 2020. Each patient had bronchial lavage, and three patients underwent thoracoscopy for the lung tissue sample taken for the culture in Sabouraud Dextrose Agar. Twelve patients were identified, 8 males and 4 females; the predominant symptoms were fever (83%), dyspnea (75%), chest pain (66%), hemoptysis (41%), and weight loss (33%). The computed tomography of the chest showed the following findings: patchy consolidation 12 (100%), hilar adenopathy 6 (50%), pleural effusion 6 (50%), caverns 3 (25%), and solitary pulmonary nodule in one patient (8%). Histoplasma capsulatum was found in the culture of all twelve patients. The signs and symptoms of the disease are mediated by the immune status of the host. The clinical picture is often confused with systemic diseases. It is important to have a high degree of clinical suspicion to make a timely diagnosis.http://dx.doi.org/10.1155/2022/2121714 |
| spellingShingle | Alejandro Hernández Solís Javier Araiza Santibáñez Jazmín Guadalupe Tejeda Olán Andrea Quintana Martínez Alejandro Hernández de la Torriente Rocio de la Torriente Mata Pulmonary Histoplasmosis in a Referral Hospital in Mexico City Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Pulmonary Histoplasmosis in a Referral Hospital in Mexico City |
| title_full | Pulmonary Histoplasmosis in a Referral Hospital in Mexico City |
| title_fullStr | Pulmonary Histoplasmosis in a Referral Hospital in Mexico City |
| title_full_unstemmed | Pulmonary Histoplasmosis in a Referral Hospital in Mexico City |
| title_short | Pulmonary Histoplasmosis in a Referral Hospital in Mexico City |
| title_sort | pulmonary histoplasmosis in a referral hospital in mexico city |
| url | http://dx.doi.org/10.1155/2022/2121714 |
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