Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases
Granulomas are rarely seen in gastric biopsies mostly as an involvement of granulomatous diseases like sarcoidosis, Crohn’s disease, infections, neoplasms, and vasculitis. Here, we claim cyanoacrylate as a foreign body type granuloma-causing agent in the stomach after vascular embolisation. We prese...
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Language: | English |
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Wiley
2017-01-01
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Series: | Case Reports in Pathology |
Online Access: | http://dx.doi.org/10.1155/2017/2753487 |
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author | Gunes Guner Olcay Kurtulan Taylan Kav Cenk Sokmensuer Gokhan Gedikoglu Aytekin Akyol |
author_facet | Gunes Guner Olcay Kurtulan Taylan Kav Cenk Sokmensuer Gokhan Gedikoglu Aytekin Akyol |
author_sort | Gunes Guner |
collection | DOAJ |
description | Granulomas are rarely seen in gastric biopsies mostly as an involvement of granulomatous diseases like sarcoidosis, Crohn’s disease, infections, neoplasms, and vasculitis. Here, we claim cyanoacrylate as a foreign body type granuloma-causing agent in the stomach after vascular embolisation. We present cyanoacrylate associated gastric changes of three cases: two endoscopic biopsies and one gastric resection. In two cases, cyanoacrylate associated ulcers and granulomatous inflammation were observed in gastric mucosal biopsies following endoscopic examination after 7 months and 6 years of the glue injections, respectively. In the third case, the cyanoacrylate injection was performed 2 months prior to the surgery. Then the patient underwent distal pancreatectomy for pancreatic adenocarcinoma and during the operation a gastric mass was resected with a suspicion of tumoral infiltration. These three cases demonstrated that glue exposure causes active chronic inflammation with foreign body type granulomas, mucosal ulceration, and bleeding in the gastric mucosa. Even further, it can induce mass formation in the injection sites. |
format | Article |
id | doaj-art-ef57cca4276444c0a7cf2adc1c92196b |
institution | Kabale University |
issn | 2090-6781 2090-679X |
language | English |
publishDate | 2017-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Pathology |
spelling | doaj-art-ef57cca4276444c0a7cf2adc1c92196b2025-02-03T06:08:11ZengWileyCase Reports in Pathology2090-67812090-679X2017-01-01201710.1155/2017/27534872753487Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three CasesGunes Guner0Olcay Kurtulan1Taylan Kav2Cenk Sokmensuer3Gokhan Gedikoglu4Aytekin Akyol5Department of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyGastroenterology Division, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyGranulomas are rarely seen in gastric biopsies mostly as an involvement of granulomatous diseases like sarcoidosis, Crohn’s disease, infections, neoplasms, and vasculitis. Here, we claim cyanoacrylate as a foreign body type granuloma-causing agent in the stomach after vascular embolisation. We present cyanoacrylate associated gastric changes of three cases: two endoscopic biopsies and one gastric resection. In two cases, cyanoacrylate associated ulcers and granulomatous inflammation were observed in gastric mucosal biopsies following endoscopic examination after 7 months and 6 years of the glue injections, respectively. In the third case, the cyanoacrylate injection was performed 2 months prior to the surgery. Then the patient underwent distal pancreatectomy for pancreatic adenocarcinoma and during the operation a gastric mass was resected with a suspicion of tumoral infiltration. These three cases demonstrated that glue exposure causes active chronic inflammation with foreign body type granulomas, mucosal ulceration, and bleeding in the gastric mucosa. Even further, it can induce mass formation in the injection sites.http://dx.doi.org/10.1155/2017/2753487 |
spellingShingle | Gunes Guner Olcay Kurtulan Taylan Kav Cenk Sokmensuer Gokhan Gedikoglu Aytekin Akyol Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases Case Reports in Pathology |
title | Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases |
title_full | Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases |
title_fullStr | Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases |
title_full_unstemmed | Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases |
title_short | Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases |
title_sort | cyanoacrylate associated foreign body granulomatous gastritis a report of three cases |
url | http://dx.doi.org/10.1155/2017/2753487 |
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