Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases

Granulomas are rarely seen in gastric biopsies mostly as an involvement of granulomatous diseases like sarcoidosis, Crohn’s disease, infections, neoplasms, and vasculitis. Here, we claim cyanoacrylate as a foreign body type granuloma-causing agent in the stomach after vascular embolisation. We prese...

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Main Authors: Gunes Guner, Olcay Kurtulan, Taylan Kav, Cenk Sokmensuer, Gokhan Gedikoglu, Aytekin Akyol
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2017/2753487
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author Gunes Guner
Olcay Kurtulan
Taylan Kav
Cenk Sokmensuer
Gokhan Gedikoglu
Aytekin Akyol
author_facet Gunes Guner
Olcay Kurtulan
Taylan Kav
Cenk Sokmensuer
Gokhan Gedikoglu
Aytekin Akyol
author_sort Gunes Guner
collection DOAJ
description Granulomas are rarely seen in gastric biopsies mostly as an involvement of granulomatous diseases like sarcoidosis, Crohn’s disease, infections, neoplasms, and vasculitis. Here, we claim cyanoacrylate as a foreign body type granuloma-causing agent in the stomach after vascular embolisation. We present cyanoacrylate associated gastric changes of three cases: two endoscopic biopsies and one gastric resection. In two cases, cyanoacrylate associated ulcers and granulomatous inflammation were observed in gastric mucosal biopsies following endoscopic examination after 7 months and 6 years of the glue injections, respectively. In the third case, the cyanoacrylate injection was performed 2 months prior to the surgery. Then the patient underwent distal pancreatectomy for pancreatic adenocarcinoma and during the operation a gastric mass was resected with a suspicion of tumoral infiltration. These three cases demonstrated that glue exposure causes active chronic inflammation with foreign body type granulomas, mucosal ulceration, and bleeding in the gastric mucosa. Even further, it can induce mass formation in the injection sites.
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id doaj-art-ef57cca4276444c0a7cf2adc1c92196b
institution Kabale University
issn 2090-6781
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language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Pathology
spelling doaj-art-ef57cca4276444c0a7cf2adc1c92196b2025-02-03T06:08:11ZengWileyCase Reports in Pathology2090-67812090-679X2017-01-01201710.1155/2017/27534872753487Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three CasesGunes Guner0Olcay Kurtulan1Taylan Kav2Cenk Sokmensuer3Gokhan Gedikoglu4Aytekin Akyol5Department of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyGastroenterology Division, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyDepartment of Pathology, Faculty of Medicine, Hacettepe University, Sıhhiye, 06100 Ankara, TurkeyGranulomas are rarely seen in gastric biopsies mostly as an involvement of granulomatous diseases like sarcoidosis, Crohn’s disease, infections, neoplasms, and vasculitis. Here, we claim cyanoacrylate as a foreign body type granuloma-causing agent in the stomach after vascular embolisation. We present cyanoacrylate associated gastric changes of three cases: two endoscopic biopsies and one gastric resection. In two cases, cyanoacrylate associated ulcers and granulomatous inflammation were observed in gastric mucosal biopsies following endoscopic examination after 7 months and 6 years of the glue injections, respectively. In the third case, the cyanoacrylate injection was performed 2 months prior to the surgery. Then the patient underwent distal pancreatectomy for pancreatic adenocarcinoma and during the operation a gastric mass was resected with a suspicion of tumoral infiltration. These three cases demonstrated that glue exposure causes active chronic inflammation with foreign body type granulomas, mucosal ulceration, and bleeding in the gastric mucosa. Even further, it can induce mass formation in the injection sites.http://dx.doi.org/10.1155/2017/2753487
spellingShingle Gunes Guner
Olcay Kurtulan
Taylan Kav
Cenk Sokmensuer
Gokhan Gedikoglu
Aytekin Akyol
Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases
Case Reports in Pathology
title Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases
title_full Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases
title_fullStr Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases
title_full_unstemmed Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases
title_short Cyanoacrylate Associated Foreign Body Granulomatous Gastritis: A Report of Three Cases
title_sort cyanoacrylate associated foreign body granulomatous gastritis a report of three cases
url http://dx.doi.org/10.1155/2017/2753487
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AT cenksokmensuer cyanoacrylateassociatedforeignbodygranulomatousgastritisareportofthreecases
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