Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn

The differential diagnosis of a congenital cutaneous vascular-appearing mass in a newborn is broad and includes both benign and malignant tumors. We report the case of a newborn who presented with an erythematous exophytic skin nodule on the right upper leg. Excision was performed due to ulceration,...

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Main Authors: Farooq Shahzad, Ava G. Chappell, Chad A. Purnell, Monica Aldulescu, Sarah Chamlin
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2019/3476508
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author Farooq Shahzad
Ava G. Chappell
Chad A. Purnell
Monica Aldulescu
Sarah Chamlin
author_facet Farooq Shahzad
Ava G. Chappell
Chad A. Purnell
Monica Aldulescu
Sarah Chamlin
author_sort Farooq Shahzad
collection DOAJ
description The differential diagnosis of a congenital cutaneous vascular-appearing mass in a newborn is broad and includes both benign and malignant tumors. We report the case of a newborn who presented with an erythematous exophytic skin nodule on the right upper leg. Excision was performed due to ulceration, concern for bleeding, and for diagnosis. Pathology revealed the mass to be an infantile myofibroma. This case highlights the importance of considering a broad differential diagnosis in a newborn with a cutaneous mass. While history, physical exam, and imaging can help diagnose some cases, a biopsy or excision is often needed to distinguish benign lesions from more concerning lesions.
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institution Kabale University
issn 2090-6803
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language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Case Reports in Pediatrics
spelling doaj-art-ef4a3c9d881b45839e1250081b4576c42025-02-03T07:24:49ZengWileyCase Reports in Pediatrics2090-68032090-68112019-01-01201910.1155/2019/34765083476508Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a NewbornFarooq Shahzad0Ava G. Chappell1Chad A. Purnell2Monica Aldulescu3Sarah Chamlin4Ann & Robert H. Lurie Children’s Hospital, Chicago, Illinois, USANorthwestern University Feinberg School of Medicine, Chicago, Illinois, USANorthwestern University Feinberg School of Medicine, Chicago, Illinois, USAAnn & Robert H. Lurie Children’s Hospital, Chicago, Illinois, USAAnn & Robert H. Lurie Children’s Hospital, Chicago, Illinois, USAThe differential diagnosis of a congenital cutaneous vascular-appearing mass in a newborn is broad and includes both benign and malignant tumors. We report the case of a newborn who presented with an erythematous exophytic skin nodule on the right upper leg. Excision was performed due to ulceration, concern for bleeding, and for diagnosis. Pathology revealed the mass to be an infantile myofibroma. This case highlights the importance of considering a broad differential diagnosis in a newborn with a cutaneous mass. While history, physical exam, and imaging can help diagnose some cases, a biopsy or excision is often needed to distinguish benign lesions from more concerning lesions.http://dx.doi.org/10.1155/2019/3476508
spellingShingle Farooq Shahzad
Ava G. Chappell
Chad A. Purnell
Monica Aldulescu
Sarah Chamlin
Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn
Case Reports in Pediatrics
title Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn
title_full Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn
title_fullStr Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn
title_full_unstemmed Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn
title_short Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn
title_sort infantile myofibroma presenting as a large ulcerative nodule in a newborn
url http://dx.doi.org/10.1155/2019/3476508
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AT chadapurnell infantilemyofibromapresentingasalargeulcerativenoduleinanewborn
AT monicaaldulescu infantilemyofibromapresentingasalargeulcerativenoduleinanewborn
AT sarahchamlin infantilemyofibromapresentingasalargeulcerativenoduleinanewborn