Pathophysiology of Portal Hypertension and Esophageal Varices
Esophageal varices are the major complication of portal hypertension. It is detected in about 50% of cirrhosis patients, and approximately 5–15% of cirrhosis patients show newly formed varices or worsening of varices each year. The major therapeutic strategy of esophageal varices consists of primary...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2012/895787 |
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| _version_ | 1832562507458281472 |
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| author | Hitoshi Maruyama Osamu Yokosuka |
| author_facet | Hitoshi Maruyama Osamu Yokosuka |
| author_sort | Hitoshi Maruyama |
| collection | DOAJ |
| description | Esophageal varices are the major complication of portal hypertension. It is detected in about 50% of cirrhosis patients, and approximately 5–15% of cirrhosis patients show newly formed varices or worsening of varices each year. The major therapeutic strategy of esophageal varices consists of primary prevention, treatment for bleeding varices, and secondary prevention, which are provided by pharmacological, endoscopic, interventional and surgical treatments. Optimal management of esophageal varices requires a clear understanding of the pathophysiology and natural history. In this paper, we outline the current knowledge and future prospect in the pathophysiology of esophageal varices and portal hypertension. |
| format | Article |
| id | doaj-art-ef3e06212f414b33909e625d089d9708 |
| institution | Kabale University |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-ef3e06212f414b33909e625d089d97082025-02-03T01:22:31ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/895787895787Pathophysiology of Portal Hypertension and Esophageal VaricesHitoshi Maruyama0Osamu Yokosuka1Department of Medicine and Clinical Oncology, Chiba University, Graduate School of Medicine, 1-8-1, Inohana, Chuo-ku, Chiba 260-8670, JapanDepartment of Medicine and Clinical Oncology, Chiba University, Graduate School of Medicine, 1-8-1, Inohana, Chuo-ku, Chiba 260-8670, JapanEsophageal varices are the major complication of portal hypertension. It is detected in about 50% of cirrhosis patients, and approximately 5–15% of cirrhosis patients show newly formed varices or worsening of varices each year. The major therapeutic strategy of esophageal varices consists of primary prevention, treatment for bleeding varices, and secondary prevention, which are provided by pharmacological, endoscopic, interventional and surgical treatments. Optimal management of esophageal varices requires a clear understanding of the pathophysiology and natural history. In this paper, we outline the current knowledge and future prospect in the pathophysiology of esophageal varices and portal hypertension.http://dx.doi.org/10.1155/2012/895787 |
| spellingShingle | Hitoshi Maruyama Osamu Yokosuka Pathophysiology of Portal Hypertension and Esophageal Varices International Journal of Hepatology |
| title | Pathophysiology of Portal Hypertension and Esophageal Varices |
| title_full | Pathophysiology of Portal Hypertension and Esophageal Varices |
| title_fullStr | Pathophysiology of Portal Hypertension and Esophageal Varices |
| title_full_unstemmed | Pathophysiology of Portal Hypertension and Esophageal Varices |
| title_short | Pathophysiology of Portal Hypertension and Esophageal Varices |
| title_sort | pathophysiology of portal hypertension and esophageal varices |
| url | http://dx.doi.org/10.1155/2012/895787 |
| work_keys_str_mv | AT hitoshimaruyama pathophysiologyofportalhypertensionandesophagealvarices AT osamuyokosuka pathophysiologyofportalhypertensionandesophagealvarices |