Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis
Purpose. Herein, we report a case of primary intraocular lymphoma (PIOL) with the first presentation of bilateral Epstein-Barr virus- (EBV-) associated panuveitis. Case Presentation. A 69-year-old male was referred with a three-day history of blurred vision and pain and redness in his left eye follo...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/9496173 |
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| author | Seyedeh Maryam Hosseini Mojtaba Abrishami Elham Barashki Ghodsieh Zamani |
| author_facet | Seyedeh Maryam Hosseini Mojtaba Abrishami Elham Barashki Ghodsieh Zamani |
| author_sort | Seyedeh Maryam Hosseini |
| collection | DOAJ |
| description | Purpose. Herein, we report a case of primary intraocular lymphoma (PIOL) with the first presentation of bilateral Epstein-Barr virus- (EBV-) associated panuveitis. Case Presentation. A 69-year-old male was referred with a three-day history of blurred vision and pain and redness in his left eye following cataract surgery. Examination revealed panuveitis, vitritis, and necrotizing retinitis with retinal hemorrhage. A month later, the right eye was also involved. Polymerase chain reaction-based analysis of the vitreous sample was positive for EBV, and cytological evaluation was compatible with the diagnosis of B-cell lymphoma. A significant improvement was observed following serial intravitreal rituximab and methotrexate injections. The central nervous system and lungs were involved after 6 months, and the patient expired despite systemic chemotherapy. Conclusion. There may be an association between EBV panuveitis and primary intraocular B-cell lymphoma. |
| format | Article |
| id | doaj-art-ef020063526c41c0af7b311d8ef85edb |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-ef020063526c41c0af7b311d8ef85edb2025-02-03T05:44:45ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/94961739496173Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus PanuveitisSeyedeh Maryam Hosseini0Mojtaba Abrishami1Elham Barashki2Ghodsieh Zamani3Eye Research Center, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranEye Research Center, Mashhad University of Medical Sciences, Mashhad, IranPurpose. Herein, we report a case of primary intraocular lymphoma (PIOL) with the first presentation of bilateral Epstein-Barr virus- (EBV-) associated panuveitis. Case Presentation. A 69-year-old male was referred with a three-day history of blurred vision and pain and redness in his left eye following cataract surgery. Examination revealed panuveitis, vitritis, and necrotizing retinitis with retinal hemorrhage. A month later, the right eye was also involved. Polymerase chain reaction-based analysis of the vitreous sample was positive for EBV, and cytological evaluation was compatible with the diagnosis of B-cell lymphoma. A significant improvement was observed following serial intravitreal rituximab and methotrexate injections. The central nervous system and lungs were involved after 6 months, and the patient expired despite systemic chemotherapy. Conclusion. There may be an association between EBV panuveitis and primary intraocular B-cell lymphoma.http://dx.doi.org/10.1155/2021/9496173 |
| spellingShingle | Seyedeh Maryam Hosseini Mojtaba Abrishami Elham Barashki Ghodsieh Zamani Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis Case Reports in Ophthalmological Medicine |
| title | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
| title_full | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
| title_fullStr | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
| title_full_unstemmed | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
| title_short | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
| title_sort | primary intraocular lymphoma in a patient with bilateral epstein barr virus panuveitis |
| url | http://dx.doi.org/10.1155/2021/9496173 |
| work_keys_str_mv | AT seyedehmaryamhosseini primaryintraocularlymphomainapatientwithbilateralepsteinbarrviruspanuveitis AT mojtabaabrishami primaryintraocularlymphomainapatientwithbilateralepsteinbarrviruspanuveitis AT elhambarashki primaryintraocularlymphomainapatientwithbilateralepsteinbarrviruspanuveitis AT ghodsiehzamani primaryintraocularlymphomainapatientwithbilateralepsteinbarrviruspanuveitis |