Identification of genes involved in verazine biosynthesis in Veratrum grandiflorum and their heterologous production in Saccharomyces cerevisiae
Abstract Verazine is a verazine-type alkaloid primarily found in plants of the family Melanthiaceae. In addition to its direct antifungal activity, it serves as a key precursor in the biosynthesis of cyclopamine, a potent inhibitor of the Hedgehog signaling pathway. In this study, we sequenced the t...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Plant Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12870-025-06899-8 |
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